Ian C. Scott

Oxidation of the alarmin IL-33 regulates ST2-dependent inflammation

E. Suzanne Cohen, Ian C. Scott, Jayesh B. Majithiya et al. · Nature Communications · 2015 · 267 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

HpARI Protein Secreted by a Helminth Parasite Suppresses Interleukin-33

Megan Osbourn, Dinesh C. Soares, Francesco Vacca et al. · Immunity · 2017 · 176 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

A stromal cell niche sustains ILC2-mediated type-2 conditioning in adipose tissue

Batika M.J. Rana, Eric Jou, Jillian L. Barlow et al. · The Journal of Experimental Medicine · 2019 · 120 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Interleukin-33 is activated by allergen- and necrosis-associated proteolytic activities to regulate its alarmin activity during epithelial damage

Ian C. Scott, Jayesh B. Majithiya, Caroline Sandén et al. · Scientific Reports · 2018 · 112 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Tozorakimab (MEDI3506): an anti-IL-33 antibody that inhibits IL-33 signalling via ST2 and RAGE/EGFR to reduce inflammation and epithelial dysfunction

Elizabeth England, D. Gareth Rees, Ian C. Scott et al. · Scientific Reports · 2023 · 109 citations · Full text

Life Sciences, Immunology, Pharmacology +17