Jun Xiao

Small Molecule Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibitors: Hit to Lead Optimization of Systemic Agents

Allyn T. Londregan, Liuqing Wei, Jun Xiao et al. · Journal of Medicinal Chemistry · 2018 · 43 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11

Physical and Functional Interactions between Lyn and p34 Kinases in Irradiated Human B-cell Precursors

Fatih M. Uckun, L Tuel-Ahlgren, Kevin G. Waddick et al. · Journal of Biological Chemistry · 1996 · 35 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

A Scalable Route for the Regio- and Enantioselective Preparation of a Tetrazole Prodrug: Application to the Multi-Gram-Scale Synthesis of a PCSK9 Inhibitor

Anne Akin, Mark T. Barrila, Thomas A. Brandt et al. · Organic Process Research & Development · 2017 · 25 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15

Hydrogen sulfide inhibits PCSK9 expression through the PI3K/Akt‑SREBP‑2 signaling pathway to influence lipid metabolism in HepG2 cells

Jun Xiao, Ling Liao, Min Zhou et al. · International Journal of Molecular Medicine · 2019 · 25 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Three Musketeers for Lowering Cholesterol: Statins, Ezetimibe and Evolocumab

Qian Xu, Yiming Deng, Jun Xiao et al. · Current Medicinal Chemistry · 2020 · 23 citations

Life Sciences, Pharmacology, Pharmacotherapy +17