Lili Zhang

Crosstalk among podocytes, glomerular endothelial cells and mesangial cells in diabetic kidney disease: an updated review

Shiwan Hu, Hang Xing, Yu Wei et al. · Cell Communication and Signaling · 2024 · 85 citations · Full text

Studies to Investigate the in Vivo Therapeutic Window of the γ-Secretase Inhibitor N2-[(2 S)-2-(3,5-Difluorophenyl)-2-hydroxyethanoyl]-N1-[(7 S)-5-methyl-6-oxo-6,7-dihydro-5 H-dibenzo[b,d]azepin-7-yl]-l-alaninamide (LY411,575) in the CRND8 Mouse

Lynn A. Hyde, Nansie A. McHugh, Joseph Chen et al. · Journal of Pharmacology and Experimental Therapeutics · 2006 · 68 citations

Design and Validation of Bicyclic Iminopyrimidinones As Beta Amyloid Cleaving Enzyme-1 (BACE1) Inhibitors: Conformational Constraint to Favor a Bioactive Conformation

Mihirbaran Mandal, Zhaoning Zhu, Jared N. Cumming et al. · Journal of Medicinal Chemistry · 2012 · 56 citations · Full text

Combinatorial Chemistry, Bicyclic Iminopyrimidinones, Pseudoaxial Conformation +21

Structure-Based Design of an Iminoheterocyclic β-Site Amyloid Precursor Protein Cleaving Enzyme (BACE) Inhibitor that Lowers Central Aβ in Nonhuman Primates

Mihirbaran Mandal, Yusheng Wu, Jeffrey Misiaszek et al. · Journal of Medicinal Chemistry · 2016 · 41 citations · Full text

Discovery of a Potent Pyrazolopyridine Series of γ-Secretase Modulators

Jun Qin, Wei Zhou, Xianhai Huang et al. · ACS Medicinal Chemistry Letters · 2011 · 34 citations · Full text