Yan Jiang

Nuclear cGAS suppresses DNA repair and promotes tumorigenesis

Haipeng Liu, Haiping Zhang, Xiangyang Wu et al. · Nature · 2018 · 617 citations

Chromatin, Genome Instability, Chromatin Remodeling +5

Structural Analysis of the STING Adaptor Protein Reveals a Hydrophobic Dimer Interface and Mode of Cyclic di-GMP Binding

Songying Ouyang, Xianqiang Song, Yaya Wang et al. · Immunity · 2012 · 325 citations · Full text

Protein Chemistry, Sting Adaptor Protein, Proteinlipid Interaction +11

Ca2+ regulates T-cell receptor activation by modulating the charge property of lipids

Xiaoshan Shi, Yunchen Bi, Wei Yang et al. · Nature · 2012 · 269 citations

Proteinlipid Interaction, Signal Transduction, Cell Signaling +12

NLRC3, a Member of the NLR Family of Proteins, Is a Negative Regulator of Innate Immune Signaling Induced by the DNA Sensor STING

Lu Zhang, Jinyao Mo, Karen V. Swanson et al. · Immunity · 2014 · 264 citations · Full text

Inflammation, Negative Regulator, Autoimmune Disease +11

Histone H3K27 methyltransferase EZH2 and demethylase JMJD3 regulate hepatic stellate cells activation and liver fibrosis

Yan Jiang, Chan Xiang, Fan Zhong et al. · Theranostics · 2020 · 118 citations · Full text