Xixin He

Design, synthesis and pharmacological evaluation of novel tacrine–caffeic acid hybrids as multi-targeted compounds against Alzheimer’s disease

Xiaojuan Chao, Xixin He, Yilin Yang et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 101 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Moracin M from Morus alba L. is a natural phosphodiesterase-4 inhibitor

Shangke Chen, Peng Zhao, Yongxian Shao et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 77 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +11

Effect of Tacrine‐3‐caffeic Acid, A Novel Multifunctional Anti‐Alzheimer's Dimer, Against Oxidative‐Stress‐Induced Cell Death in <scp>HT</scp>22 Hippocampal Neurons: Involvement of Nrf2/<scp>HO</scp>‐1 Pathway

Xiaojuan Chao, Ziwei Chen, Anmin Liu et al. · CNS Neuroscience & Therapeutics · 2014 · 53 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

Discovery and Optimization of α-Mangostin Derivatives as Novel PDE4 Inhibitors for the Treatment of Vascular Dementia

Jinhao Liang, Yi‐You Huang, Qian Zhou et al. · Journal of Medicinal Chemistry · 2020 · 52 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

Mangostanin Derivatives as Novel and Orally Active Phosphodiesterase 4 Inhibitors for the Treatment of Idiopathic Pulmonary Fibrosis with Improved Safety

Yi‐You Huang, Jinhui Deng, Yi‐Jing Tian et al. · Journal of Medicinal Chemistry · 2021 · 44 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14