Concepedia

Design, synthesis and pharmacological evaluation of novel tacrine–caffeic acid hybrids as multi-targeted compounds against Alzheimer’s disease

Xiaojuan Chao, Xixin He, Yilin Yang, Xie Zhou, Minghua Jin, Shu Liu, Zhiyi Cheng, Peiqing Liu, Yuting Wang, Jianchen Yu,

Bioorganic & Medicinal Chemistry Letters · 2012 · 101 citations · 23 references

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References

23

Quaternary ligand binding to aromatic residues in the active-site gorge of acetylcholinesterase.

Michal Harel, Isabelle J. Schalk, Laurence Ehret‐Sabatier et al. · Proceedings of the National Academy of Sciences · 1993 · 903 citations

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Cu(II) Potentiation of Alzheimer Aβ Neurotoxicity

Xudong Huang, Math P. Cuajungco, Craig Atwood et al. · Journal of Biological Chemistry · 1999 · 760 citations · Full text

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Novel and therapeutic effect of caffeic acid and caffeic acid phenyl ester on hepatocarcinoma cells: complete regression of hepatoma growth and metastasis by dual mechanism

Tae‐Wook Chung, Sung‐Kwon Moon, Young‐Chae Chang et al. · The FASEB Journal · 2004 · 457 citations

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Inhibition of Activator Protein-1, NF-κB, and MAPKs and Induction of Phase 2 Detoxifying Enzyme Activity by Chlorogenic Acid

Rentian Feng, Yongju Lu, Linda Bowman et al. · Journal of Biological Chemistry · 2005 · 388 citations · Full text

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Highly Potent, Selective, and Low Cost Bis-tetrahydroaminacrine Inhibitors of Acetylcholinesterase

Yuan‐Ping Pang, Polly A. Quiram, Tanya M. Jelacic et al. · Journal of Biological Chemistry · 1996 · 346 citations · Full text

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