Zheying Huang

The comparison of ZFNs, TALENs, and SpCas9 by GUIDE-seq in HPV-targeted gene therapy

Zifeng Cui, Hui Liu, Hongfeng Zhang et al. · Molecular Therapy — Nucleic Acids · 2021 · 51 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

FrCas9 is a CRISPR/Cas9 system with high editing efficiency and fidelity

Zifeng Cui, Rui Tian, Zhaoyue Huang et al. · Nature Communications · 2022 · 42 citations · Full text

Life Sciences, Biotechnology, Genetics +17

HPV integration generates a cellular super-enhancer which functions as ecDNA to regulate genome-wide transcription

Rui Tian, Zheying Huang, Lifang Li et al. · Nucleic Acids Research · 2023 · 40 citations · Full text

Medicine, Molecular Biology, Oncology +17

Gene knock-out chain reaction enables high disruption efficiency of HPV18 E6/E7 genes in cervical cancer cells

Rui Tian, Jiashuo Liu, Weiwen Fan et al. · Molecular Therapy — Oncolytics · 2021 · 31 citations · Full text

Life Sciences, Biotechnology, Genetics +17

Massively parallel CRISPR off-target detection enables rapid off-target prediction model building

Rui Tian, Chen Cao, Dan He et al. · Med · 2023 · 23 citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +6