Distribution, transformation and toxicity evaluation of 2,6-Di-tert-butyl-hydroxytotulene in aquatic environment

Yan Wang, Lin He, Guochun Lv, +4

Environmental Pollution

Environmental ChemistryEcotoxicityEngineeringEnvironmental EngineeringWater Treatment +8

The comparison of ZFNs, TALENs, and SpCas9 by GUIDE-seq in HPV-targeted gene therapy

Zifeng Cui, Hui Liu, Hongfeng Zhang, +21

Molecular Therapy — Nucleic Acids

Magnetic field-enhanced radical intensity for accelerating norfloxacin degradation under FeCu/rGO photo-Fenton catalysis

Hongbing Dan, Yan Kong, Qinyan Yue, +5

Chemical Engineering Journal

Oxygen Reduction ReactionAdvanced Oxidation ProcessChemical EngineeringEngineeringPhotochemistry +7

FrCas9 is a CRISPR/Cas9 system with high editing efficiency and fidelity

Zifeng Cui, Rui Tian, Zhaoyue Huang, +12

Nature Communications

HPV integration generates a cellular super-enhancer which functions as ecDNA to regulate genome-wide transcription

Rui Tian, Zheying Huang, Lifang Li, +14

Nucleic Acids Research

Gene knock-out chain reaction enables high disruption efficiency of HPV18 E6/E7 genes in cervical cancer cells

Rui Tian, Jiashuo Liu, Weiwen Fan, +10

Molecular Therapy — Oncolytics

Massively parallel CRISPR off-target detection enables rapid off-target prediction model building

Rui Tian, Chen Cao, Dan He, +14

Med

Off-target EffectEngineeringGeneticsComputational GenomicsComputational Biology +8

Aminotriazole Alleviates Acetaminophen Poisoning via Downregulating P450 2E1 and Suppressing Inflammation

Yuping Jing, Kunwei Wu, Jiashuo Liu, +8

PLoS ONE

PharmacotherapyDownregulating P450 2E1Experimental PharmacologyRedox BiologyToxicological Mechanism +20

A Cas12a ortholog with distinct TTNA PAM enables sensitive detection of HPV16/18

Ye Chen, Lirong Meng, Bin Lang, +7

Cell Reports Methods

Hesperidin ameliorates H2O2-induced bovine mammary epithelial cell oxidative stress via the Nrf2 signaling pathway

Qi Huang, Jiashuo Liu, Can Peng, +2

Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology