Mechanism of allosteric modulation of P-glycoprotein by transport substrates and inhibitors

Reza Dastvan, Smriti Mishra, Yelena Peskova, +2

Science

Conformational dynamics of the nucleotide binding domains and the power stroke of a heterodimeric ABC transporter

Smriti Mishra, Brandy Verhalen, Richard A. Stein, +3

eLife

Lipids modulate the conformational dynamics of a secondary multidrug transporter

Chloé Martens, Richard A. Stein, Matthieu Masureel, +7

Nature Structural & Molecular Biology

Conformational DynamicsProteinlipid InteractionBiochemistryNatural SciencesMembrane Transport +5

Protonation drives the conformational switch in the multidrug transporter LmrP

Matthieu Masureel, Chloé Martens, Richard A. Stein, +4

Nature Chemical Biology

BiochemistryProton TransferProton-coupled Electron TransferConformational SwitchMembrane Biology +2

Unfolding of a Temperature-Sensitive Domain Controls Voltage-Gated Channel Activation

Cristina Arrigoni, Ahmed Rohaim, David Shaya, +6

Cell

Bias Temperature InstabilityElectrical Engineering

Protonation-dependent conformational dynamics of the multidrug transporter EmrE

Reza Dastvan, Axel W. Fischer, Smriti Mishra, +2

Proceedings of the National Academy of Sciences

Navigating Membrane Protein Structure, Dynamics, and Energy Landscapes Using Spin Labeling and EPR Spectroscopy

Derek P. Claxton, Kelli Kazmier, Smriti Mishra, +1

Methods in enzymology on CD-ROM/Methods in enzymology

Proteinlipid InteractionMembrane BiophysicsBiochemistryBiomolecular Structure PredictionProtein Folding +10

Probing the solution structure of the E. coli multidrug transporter MdfA using DEER distance measurements with nitroxide and Gd(III) spin labels

Eliane Hadas Yardeni, Thorsten Bahrenberg, Richard A. Stein, +8

Scientific Reports

Direct Spectroscopic Detection of ATP Turnover Reveals Mechanistic Divergence of ABC Exporters

Alberto Collauto, Smriti Mishra, Aleksei Litvinov, +2

Structure

BiochemistryBioenergeticsNatural SciencesBiomolecular AnalysisMolecular Biology +6

Elucidation of stable intermediates in urea-induced unfolding pathway of human carbonic anhydrase IX

Amresh Prakash, Gunjan Dixit, Naveen Kumar Meena, +4

Journal of Biomolecular Structure and Dynamics

Molecular BiologyAnalytical UltracentrifugationMolecular DynamicsStructural Snap ShotUrea-induced Unfolding Pathway +23