David Shaya

Complexes of Alkylene-Linked Tacrine Dimers with <i>Torpedo c</i><i>alifornica</i> Acetylcholinesterase:  Binding of Bis(5)-tacrine Produces a Dramatic Rearrangement in the Active-Site Gorge

Edwin H. Rydberg, Boris Brumshtein, Harry M. Greenblatt et al. · Journal of Medicinal Chemistry · 2006 · 189 citations · Full text

7-Carbon Spacer, Engineering, Molecular Biology +19

Structure of a Prokaryotic Sodium Channel Pore Reveals Essential Gating Elements and an Outer Ion Binding Site Common to Eukaryotic Channels

David Shaya, Felix Findeisen, Fayal Abderemane-Ali et al. · Journal of Molecular Biology · 2013 · 139 citations · Full text

Crystal Structure of Heparinase II from Pedobacter heparinus and Its Complex with a Disaccharide Product

David Shaya, Ante Tocilj, Yunge Li et al. · Journal of Biological Chemistry · 2006 · 97 citations · Full text

Crystal Structure, Pedobacter Heparinus, Heparin Degradation +14

Voltage-gated sodium channel (Na_V) protein dissection creates a set of functional pore-only proteins

David Shaya, Mohamed Kreir, Rebecca A. Robbins et al. · Proceedings of the National Academy of Sciences · 2011 · 89 citations · Full text

Proteinlipid Interaction, Protein Secretion, Molecular Biology +23

Structural Snapshots of Heparin Depolymerization by Heparin Lyase I

Young-Hyun Han, Marie-Line Garron, Hye‐Yeon Kim et al. · Journal of Biological Chemistry · 2009 · 75 citations · Full text

Protein Chemistry, Heparin Depolymerization, Protein Assembly +14