Patricia Macedo

Efficacy and safety of the elexacaftor plus tezacaftor plus ivacaftor combination regimen in people with cystic fibrosis homozygous for the F508del mutation: a double-blind, randomised, phase 3 trial

Harry Heijerman, Edward F. McKone, D.G. Downey et al. · The Lancet · 2019 · 1.3K citations · Full text

Mendelian Disorder, Genetics, Ivacaftor Combination Regimen +2

Transcriptome analysis shows activation of circulating CD8+ T cells in patients with severe asthma

Eleni Tsitsiou, Andrew E. Williams, Sterghios Moschos et al. · Journal of Allergy and Clinical Immunology · 2011 · 193 citations · Full text

Asthma, Inflammation, Transcriptome Analysis +10

Chest radiography is a poor predictor of respiratory symptoms and functional impairment in survivors of severe COVID-19 pneumonia

Rebecca D’Cruz, Michael D Waller, Felicity Perrin et al. · ERJ Open Research · 2020 · 182 citations · Full text

Diminished sarco/endoplasmic reticulum Ca²⁺ATPase (SERCA) expression contributes to airway remodelling in bronchial asthma

Katharina Mahn, Stuart J. Hirst, Ying Sun et al. · Proceedings of the National Academy of Sciences · 2009 · 149 citations · Full text

Asthma, Inflammatory Lung Disease, Healthy Subjects +18

Inflammatory biomarkers in airways of patients with severe asthma compared with non‐severe asthma

Patricia Macedo, Mark Hew, Alfons Torregó et al. · Clinical & Experimental Allergy · 2009 · 75 citations