Inflammatory biomarkers in airways of patients with severe asthma compared with non‐severe asthma

Patricia Macedo, Mark Hew, Alfons Torregó, S. Jouneau, Thomas W. Oates, Andrew Durham, Kian Fan Chung

Clinical & Experimental Allergy · 2009 · 75 citations · 20 references

Abstract

Differences in inflammatory cells were observed mainly in terms of increased neutrophils and reduction in macrophage numbers in BAL fluid with a trend towards increased eosinophils in severe asthma compared with non-severe asthma. However, the most notable features are the increase in features of airway wall remodelling of SBM thickness and smooth muscle area.

References

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