Concepedia

Xiaoyi Deng

XD

Statistics

Publications

25

Citations

1.9K

H-Index

20

Active since

2007

Affiliations

The University of Texas Southwestern Medical Center(Current)

University of Washington

Medicines for Malaria Venture

Monash University

Swiss Tropical and Public Health Institute

Xiaoyi Deng is an author at The University of Texas Southwestern Medical Center specializing in enzyme inhibition, pharmacology, and medicinal chemistry.

ORCID

Publications per year

2007–2024

25

Publications

25

A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria

Margaret A. Phillips, Julie Lotharius, Kennan C. Marsh et al. · Science Translational Medicine · 2015 · 375 citations

, , +9

Structure-Guided Lead Optimization of Triazolopyrimidine-Ring Substituents Identifies Potent<i>Plasmodium falciparum</i>Dihydroorotate Dehydrogenase Inhibitors with Clinical Candidate Potential

José M. Coterón, María Marco, Jorge Esquivias et al. · Journal of Medicinal Chemistry · 2011 · 284 citations · Full text

, , +17

Lead Optimization of Aryl and Aralkyl Amine-Based Triazolopyrimidine Inhibitors of<i>Plasmodium falciparum</i>Dihydroorotate Dehydrogenase with Antimalarial Activity in Mice

Ramesh Gujjar, Farah El Mazouni, Karen L. White et al. · Journal of Medicinal Chemistry · 2011 · 167 citations · Full text

, , +17

Novel Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase with Anti-malarial Activity in the Mouse Model*

Michael L. Booker, Cecilia M. Bastos, Martin Kramer et al. · Journal of Biological Chemistry · 2010 · 136 citations · Full text

, , +16

Structural Plasticity of Malaria Dihydroorotate Dehydrogenase Allows Selective Binding of Diverse Chemical Scaffolds

Xiaoyi Deng, Ramesh Gujjar, Farah El Mazouni et al. · Journal of Biological Chemistry · 2009 · 123 citations · Full text

, , +14

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