Concepedia

Xiaoyi Deng

XD

24

Publications

1.9K

Citations

20

H-Index

2007

Active since

Affiliations

The University of Texas Southwestern Medical Center(Current)

University of Washington

Medicines for Malaria Venture

Monash University

Swiss Tropical and Public Health Institute

Xiaoyi Deng is an author at The University of Texas Southwestern Medical Center specializing in medicine, biochemistry, and molecular biology.

ORCID

Top concepts

Publications per year

2007–2024

24

Publications

24

A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria

Margaret A. Phillips, Julie Lotharius, Kennan C. Marsh et al. · Science Translational Medicine · 2015 · 367 citations

Structure-Guided Lead Optimization of Triazolopyrimidine-Ring Substituents Identifies Potent<i>Plasmodium falciparum</i>Dihydroorotate Dehydrogenase Inhibitors with Clinical Candidate Potential

José M. Coterón, María Marco, Jorge Esquivias et al. · Journal of Medicinal Chemistry · 2011 · 280 citations · Full text

Lead Optimization of Aryl and Aralkyl Amine-Based Triazolopyrimidine Inhibitors of<i>Plasmodium falciparum</i>Dihydroorotate Dehydrogenase with Antimalarial Activity in Mice

Ramesh Gujjar, Farah El Mazouni, Karen L. White et al. · Journal of Medicinal Chemistry · 2011 · 165 citations · Full text

Novel Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase with Anti-malarial Activity in the Mouse Model*

Michael L. Booker, Cecilia M. Bastos, Martin Kramer et al. · Journal of Biological Chemistry · 2010 · 134 citations · Full text

Structural Plasticity of Malaria Dihydroorotate Dehydrogenase Allows Selective Binding of Diverse Chemical Scaffolds

Xiaoyi Deng, Ramesh Gujjar, Farah El Mazouni et al. · Journal of Biological Chemistry · 2009 · 122 citations · Full text

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