Hiroshi Kiyono

Helper T cell subsets for immunoglobulin A responses: oral immunization with tetanus toxoid and cholera toxin as adjuvant selectively induces Th2 cells in mucosa associated tissues.

J Xu-Amano, Hiroshi Kiyono, R J Jackson et al. · The Journal of Experimental Medicine · 1993 · 451 citations · Full text

Life Sciences, Immunology, Cellular Immunology +16

Mucosal adjuvant effect of cholera toxin in mice results from induction of T helper 2 (Th2) cells and IL-4

Mariarosaria Marinaro, Herman F. Staats, Takachika Hiroi et al. · The Journal of Immunology · 1995 · 390 citations

Life Sciences, Immunology, Pathobiology +17

Oral immunization of interleukin-4 (IL-4) knockout mice with a recombinant Salmonella strain or cholera toxin reveals that CD4+ Th2 cells producing IL-6 and IL-10 are associated with mucosal immunoglobulin A responses

Nobuo Okahashi, Masafumi Yamamoto, John L. VanCott et al. · Infection and Immunity · 1996 · 178 citations · Full text

Life Sciences, Immunology, Infectious Diseases +17

Novel function for intestinal intraepithelial lymphocytes. Murine CD3+, gamma/delta TCR+ T cells produce IFN-gamma and IL-5

Takashi Taguchi, Wilhelm K. Aicher, Keiko Fujihashi et al. · The Journal of Immunology · 1991 · 175 citations

Life Sciences, Cell Biology, Immunology +17

Mechanisms for Mucosal Immunogenicity and Adjuvancy of Escherichia coli Labile Enterotoxin

Ichiro Takahashi, Mariarosaria Marinaro, Hiroshi Kiyono et al. · The Journal of Infectious Diseases · 1996 · 175 citations

Life Sciences, Immunology, Cellular Immunology +16