Zhonghua Luo

Discovery of hepatitis B virus capsid assembly inhibitors leading to a heteroaryldihydropyrimidine based clinical candidate (GLS4)

Qingyun Ren, Xinchang Liu, Zhonghua Luo et al. · Bioorganic & Medicinal Chemistry · 2016 · 56 citations · Full text

Viral Hepatitis, Medicine, Antiviral Drug Development +8

Highly Enantioselective Synthesis of <i>syn</i>-β-Hydroxy α-Dibenzylamino Esters via DKR Asymmetric Transfer Hydrogenation and Gram-Scale Preparation of Droxidopa

Guodong Sun, Zihong Zhou, Zhonghua Luo et al. · Organic Letters · 2017 · 43 citations

Asymmetric Transfer Hydrogenation, Excellent Diastereoselectivity, Engineering +11

3-((<i>R</i>)-4-(((<i>R</i>)-6-(2-Bromo-4-fluorophenyl)-5-(ethoxycarbonyl)-2-(thiazol-2-yl)-3,6-dihydropyrimidin-4-yl)methyl)morpholin-2-yl)propanoic Acid (HEC72702), a Novel Hepatitis B Virus Capsid Inhibitor Based on Clinical Candidate GLS4

Qingyun Ren, Xinchang Liu, Guanghua Yan et al. · Journal of Medicinal Chemistry · 2018 · 35 citations · Full text

Immunology, Chronic Hepatitis B, Antiviral Drug +17

Development of an Efficient and Scalable Biocatalytic Route to (3<i>R</i>)-3-Aminoazepane: A Pharmaceutically Important Intermediate

Yahui Feng, Zhonghua Luo, Guodong Sun et al. · Organic Process Research & Development · 2017 · 28 citations

Combinatorial Chemistry, Engineering, Organic Chemistry +17

Development of an Efficient and Scalable Asymmetric Synthesis of Eliglustat via Ruthenium(II)-Catalyzed Asymmetric Transfer Hydrogenation

Guodong Sun, Weilin Jian, Zhonghua Luo et al. · Organic Process Research & Development · 2019 · 25 citations

Engineering, Organic Chemistry, Chemistry +19