Qingyun Ren

Preclinical Characterization of GLS4, an Inhibitor of Hepatitis B Virus Core Particle Assembly

Guoyi Wu, Bo Liu, Yingjun Zhang et al. · Antimicrobial Agents and Chemotherapy · 2013 · 121 citations · Full text

Discovery of hepatitis B virus capsid assembly inhibitors leading to a heteroaryldihydropyrimidine based clinical candidate (GLS4)

Qingyun Ren, Xinchang Liu, Zhonghua Luo et al. · Bioorganic & Medicinal Chemistry · 2016 · 56 citations · Full text

Viral Hepatitis, Medicine, Antiviral Drug Development +8

A First-in-Human Trial of GLS4, a Novel Inhibitor of Hepatitis B Virus Capsid Assembly, following Single- and Multiple-Ascending-Oral-Dose Studies with or without Ritonavir in Healthy Adult Volunteers

Nan Zhao, Bo Jia, Hong Zhao et al. · Antimicrobial Agents and Chemotherapy · 2019 · 45 citations · Full text

Healthy Adult Volunteers, First-in-human Trial, Antiviral Compound +15

3-((<i>R</i>)-4-(((<i>R</i>)-6-(2-Bromo-4-fluorophenyl)-5-(ethoxycarbonyl)-2-(thiazol-2-yl)-3,6-dihydropyrimidin-4-yl)methyl)morpholin-2-yl)propanoic Acid (HEC72702), a Novel Hepatitis B Virus Capsid Inhibitor Based on Clinical Candidate GLS4

Qingyun Ren, Xinchang Liu, Guanghua Yan et al. · Journal of Medicinal Chemistry · 2018 · 35 citations · Full text

Immunology, Chronic Hepatitis B, Antiviral Drug +17

Facile synthesis and herbicidal activity of novel multisubstituted pyridine derivatives

Qingyun Ren, Wenyan Mo, Ling Gao et al. · Journal of Heterocyclic Chemistry · 2010 · 28 citations

Pyridine Derivatives, Derivative (Chemistry), Bioorganic Chemistry +14