Zhiru Yang

GFRAL is the receptor for GDF15 and is required for the anti-obesity effects of the ligand

Linda Yang, Chih-Chuan Chang, Zhe Sun et al. · Nature Medicine · 2017 · 633 citations

Obesity, Metabolic Syndrome, Molecular Physiology +10

Crystal Structure of the Carboxyltransferase Domain of Acetyl-Coenzyme A Carboxylase

Hailong Zhang, Zhiru Yang, Yang Shen et al. · Science · 2003 · 180 citations

Structure of UL18, a peptide-binding viral MHC mimic, bound to a host inhibitory receptor

Zhiru Yang, Pamela J. Björkman · Proceedings of the National Academy of Sciences · 2008 · 97 citations · Full text

Crystal Structure, Protein Assembly, Immunology +17

NK cell-derived exosomes enhance the anti-tumor effects against ovarian cancer by delivering cisplatin and reactivating NK cell functions

Heyong Luo, Yanhua Zhou, Jing Zhang et al. · Frontiers in Immunology · 2023 · 82 citations · Full text

Nk Cell-derived Exosomes, Nk Cell Functions, Immunology +17

Structure of a closed form of human malic enzyme and implications for catalytic mechanism.

Liang Tong, Zhiru Yang, Daniel L. Floyd et al. · Nature Structural Biology · 2000 · 77 citations

Biochemistry, Natural Sciences, Enzyme Catalysis +7