Dong-Ki Choi

Antibody targeting intracellular oncogenic Ras mutants exerts anti-tumour effects after systemic administration

Seungmin Shin, Dong-Ki Choi, Keun‐Ok Jung et al. · Nature Communications · 2017 · 147 citations · Full text

Medicine, Oncology, Pharmacology +16

Cellular Internalization Mechanism and Intracellular Trafficking of Filamentous M13 Phages Displaying a Cell-Penetrating Transbody and TAT Peptide

Aeyung Kim, Tae Hwan Shin, Seungmin Shin et al. · PLoS ONE · 2012 · 74 citations · Full text

Life Sciences, Microbiology, Molecular Biology +17

A general strategy for generating intact, full-length IgG antibodies that penetrate into the cytosol of living cells

Dong-Ki Choi, Jeomil Bae, Seung-Min Shin et al. · mAbs · 2014 · 71 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Direct targeting of oncogenic RAS mutants with a tumor-specific cytosol-penetrating antibody inhibits RAS mutant–driven tumor growth

Seungmin Shin, Ji‐Sun Kim, Seong-Wook Park et al. · Science Advances · 2020 · 63 citations · Full text

Medicine, Oncology, Pharmacology +17

Endosomal acidic pH-induced conformational changes of a cytosol-penetrating antibody mediate endosomal escape

Jisun Kim, Dong-Ki Choi, Ju-Yeon Shin et al. · Journal of Controlled Release · 2016 · 59 citations

Life Sciences, Biochemistry, Molecular Biology +14