Hiroshi Kiwada

Injection of PEGylated liposomes in rats elicits PEG-specific IgM, which is responsible for rapid elimination of a second dose of PEGylated liposomes

Tatsuhiro Ishida, Masako Ichihara, Xinyu Wang et al. · Journal of Controlled Release · 2006 · 542 citations

Lipid Preparation, Peg-specific Igm, Medicine +6

The size of liposomes: a factor which affects their targeting efficiency to tumors and therapeutic activity of liposomal antitumor drugs

Atsushi Nagayasu, Kazuko Uchiyama, Hiroshi Kiwada · Advanced Drug Delivery Reviews · 1999 · 436 citations

Drug Targeting, Exosomes, Liposomal Antitumor Drugs +10

Anti-PEG IgM elicited by injection of liposomes is involved in the enhanced blood clearance of a subsequent dose of PEGylated liposomes

Xinyu Wang, Tatsuhiro Ishida, Hiroshi Kiwada · Journal of Controlled Release · 2007 · 410 citations

Lipid Preparation, Translational Medicine, Medicine +7

PEGylated liposomes elicit an anti-PEG IgM response in a T cell-independent manner

Tatsuhiro Ishida, Xinyu Wang, Taro Shimizu et al. · Journal of Controlled Release · 2007 · 375 citations

Anti-peg Igm Response, Cell Trafficking, Immunology +9

Accelerated blood clearance of PEGylated liposomes following preceding liposome injection: Effects of lipid dose and PEG surface-density and chain length of the first-dose liposomes

Tatsuhiro Ishida, Masae Harada, Xinyu Wang et al. · Journal of Controlled Release · 2005 · 355 citations

Lipid Preparation, Chain Length, Lipid Dose +7