Kazutsune Yamagata

Bloom’s and Werner’s syndrome genes suppress hyperrecombination in yeast <i>sgs1</i> mutant: Implication for genomic instability in human diseases

Kazutsune Yamagata, Junichi Kato, Akira Shimamoto et al. · Proceedings of the National Academy of Sciences · 1998 · 296 citations · Full text

Medicine, Genetics, Molecular Genetics +17

Selective inhibition of mutant IDH1 by DS-1001b ameliorates aberrant histone modifications and impairs tumor activity in chondrosarcoma

Makoto Nakagawa, Fumihiko Nakatani, Hironori Matsunaga et al. · Oncogene · 2019 · 69 citations · Full text

Medicine, Oncology, Pharmacology +14

Sirt1 physically interacts with Tip60 and negatively regulates Tip60-mediated acetylation of H2AX

Kazutsune Yamagata, Issay Kitabayashi · Biochemical and Biophysical Research Communications · 2009 · 67 citations

Life Sciences, Biochemistry, Molecular Biology +8

A Potent Blood–Brain Barrier-Permeable Mutant IDH1 Inhibitor Suppresses the Growth of Glioblastoma with IDH1 Mutation in a Patient-Derived Orthotopic Xenograft Model

Yukino Machida, Makoto Nakagawa, Hironori Matsunaga et al. · Molecular Cancer Therapeutics · 2019 · 55 citations · Full text

Medicine, Oncology, Pharmacology +15

EPC1/TIP60-Mediated Histone Acetylation Facilitates Spermiogenesis in Mice

Yixin Dong, Kyoichi Isono, Kazuyuki Ohbo et al. · Molecular and Cellular Biology · 2017 · 43 citations · Full text

Life Sciences, Genetics, Molecular Biology +16