Mark J. Hughes

2-Metallated Oxazoles; pKa Dependent Deuterations, NMR Studies and Palladium Catalysed Coupling.

Eleanor A. Crowe, Frank Hossner, Mark J. Hughes · Tetrahedron · 1995 · 50 citations

Chemical Engineering, Cross-coupling Reaction, Engineering +7

ATP-citrate-lyase as a target for hypolipidemic intervention. Sulfoximine and 3-hydroxy-.beta.-lactam containing analogs of citric acid as potential tight-binding inhibitors

Roland E. Dolle, David McNair, Mark J. Hughes et al. · Journal of Medicinal Chemistry · 1992 · 22 citations · Full text

Methionine Sulfoximine, Atp-citrate Lyase, Pharmacotherapy +18

Preparation and alkylation of N-t-butyldimethylsilyl-3-trimethylsilyloxyazetidin-2-one

Roland E. Dolle, Mark J. Hughes, Chun-Sing Li et al. · Journal of the Chemical Society Chemical Communications · 1989 · 20 citations

Chemical Engineering, M. J. Hughes, Engineering +8

Milbemycin synthesis: synthesis of a macrocyclic analogue of non-aromatic β-milbemycins

Mark J. Hughes, Eric J. Thomas · Journal of the Chemical Society Perkin Transactions 1 · 1993 · 16 citations

Medicinal Chemistry, Hydroxycyclohexanone 16, Natural Sciences +15