Single-cell multiomics sequencing and analyses of human colorectal cancer

Shuhui Bian, Yu Hou, Xin Zhou, +18

Science

Single-Cell Multiomics Sequencing Reveals Prevalent Genomic Alterations in Tumor Stromal Cells of Human Colorectal Cancer

Yuan Zhou, Shuhui Bian, Xin Zhou, +6

Cancer Cell

Tumor BiologyTumor HeterogeneityMedicineSingle Cell SequencingColorectal Cancer +11

Tracing the temporal-spatial transcriptome landscapes of the human fetal digestive tract using single-cell RNA-sequencing

Shuai Gao, Liying Yan, Rui Wang, +20

Nature Cell Biology

EngineeringTranscriptomics TechnologyGenomicsSpatial OmicsTrajectory Analysis +14

A PROTAC peptide induces durable β-catenin degradation and suppresses Wnt-dependent intestinal cancer

Hongwei Liao, Xiang Li, Lianzheng Zhao, +8

Cell Discovery

Clinical translational evaluation of Al18F-NOTA-FAPI for fibroblast activation protein-targeted tumour imaging

Xin Zhou, Xiaoxia Xu, Jin Ding, +5

European Journal of Nuclear Medicine and Molecular Imaging

Tumor BiologyEngineeringOncologic ImagingMedicineBiomedical Imaging +10

Single-cell genomic and transcriptomic landscapes of primary and metastatic colorectal cancer tumors

Rui Wang, Jingyun Li, Xin Zhou, +12

Genome Medicine

Systematic evaluation of colorectal cancer organoid system by single-cell RNA-Seq analysis

Rui Wang, Yunuo Mao, Wendong Wang, +7

Genome biology

Drug repurposing screening and mechanism analysis based on human colorectal cancer organoids

Yunuo Mao, Wei Wang, Jingwei Yang, +7

Protein & Cell

Deficiency of the X-inactivation escaping gene <i>KDM5C</i> in clear cell renal cell carcinoma promotes tumorigenicity by reprogramming glycogen metabolism and inhibiting ferroptosis

Qian Zheng, Pengfei Li, Xin Zhou, +9

Theranostics

Genomic and transcriptomic profiling of carcinogenesis in patients with familial adenomatous polyposis

Jingyun Li, Rui Wang, Xin Zhou, +9

Gut