The protective effect of dexmedetomidine on LPS-induced acute lung injury through the HMGB1-mediated TLR4/NF-κB and PI3K/Akt/mTOR pathways

Meng Lu, Longyun Li, Shan Lu, +6

Molecular Immunology

Acute Lung InjuryPi3k/akt/mtor PathwaysInflammatory Lung DiseaseLung InflammationImmunology +14

LncRNA NONRATT021972 Was Associated with Neuropathic Pain Scoring in Patients with Type 2 Diabetes

Wei Yu, Guoqing Zhao, Rangjuan Cao, +2

Behavioural Neurology

Muscone relieves inflammatory pain by inhibiting microglial activation-mediated inflammatory response via abrogation of the NOX4/JAK2-STAT3 pathway and NLRP3 inflammasome

Shanshan Yu, Guoqing Zhao, Fanglei Han, +4

International Immunopharmacology

InflammationPain ResearchNox4/jak2-stat3 PathwayAnti-inflammatoryHealth Sciences +9

Ketamine Inhibits Ovarian Cancer Cell Growth by Regulating the lncRNA-PVT1/EZH2/p57 Axis

Tao Li, Jie Yang, Ben Yang, +6

Frontiers in Genetics

Lncrna Pvt1Geo DatasetCancer BiologyEpigeneticsTumor Biology +16

Lipidomic profiling reveals distinct differences in plasma lipid composition in healthy, prediabetic, and type 2 diabetic individuals

Huanzi Zhong, Chao Fang, Yanqun Fan, +24

GigaScience

Anesthesia/Surgery Induces Cognitive Impairment in Female Alzheimer’s Disease Transgenic Mice

Ce Zhang, Yiying Zhang, Yuan Shen, +3

Journal of Alzheimer s Disease

Neurodegenerative DiseasesNeuropsychologyAlzheimer's DiseaseBrain FunctionBrain Health +13

Beclin1-mediated ferroptosis activation is associated with isoflurane-induced toxicity in SH-SY5Y neuroblastoma cells

Ruizhu Liu, Xuefeng Li, Guoqing Zhao

Acta Biochimica et Biophysica Sinica

Lipid PeroxidationApoptosisCell DeathRedox BiologyToxicological Mechanism +22

Downregulation of microRNA-218 relieves neuropathic pain by regulating suppressor of cytokine signaling 3

Longyun Li, Guoqing Zhao

International Journal of Molecular Medicine

Pain TherapyPain MedicineImmunologyNeuropathic PainPathology +16

Epigenetic upregulation of Cdk5 in the dorsal horn contributes to neuropathic pain in rats

Kai Li, Guoqing Zhao, Longyun Li, +2

Neuroreport

Epigenetic UpregulationPain MedicineCdk5 Promoter RegionNeuropathic PainMolecular Pain +15

Inhibition of MicroRNA-15a/16 Expression Alleviates Neuropathic Pain Development through Upregulation of G Protein-Coupled Receptor Kinase 2

Tao Li, Yingchun Wan, Shoujun Tao, +5

Biomolecules & Therapeutics