The protective effect of dexmedetomidine on LPS-induced acute lung injury through the HMGB1-mediated TLR4/NF-κB and PI3K/Akt/mTOR pathways

Meng Lu, Longyun Li, Shan Lu, +6

Molecular Immunology

Acute Lung InjuryPi3k/akt/mtor PathwaysInflammatory Lung DiseaseLung InflammationImmunology +14

Antioxidant capacity of flavonoids from Folium Artemisiae Argyi and the molecular mechanism in Caenorhabditis elegans

Qian Hu, Zegan Liu, Yujie Guo, +3

Journal of Ethnopharmacology

PolyphenolicsBiochemistryMedicineMolecular MechanismPhytochemical +6

IL-6 promotes epithelial-to-mesenchymal transition of human peritoneal mesothelial cells possibly through the JAK2/STAT3 signaling pathway

Jing Xiao, Yanan Gong, Ying Chen, +10

American Journal of Physiology-Renal Physiology

Jak2/stat3 PathwayImmunologyImmunologic MechanismDialysis TherapyImmune System +14

<p>Long Noncoding RNA <em>EBLN3P</em> Promotes the Progression of Liver Cancer via Alteration of microRNA-144-3p/DOCK4 Signal</p>

Hang Li, Min Wang, Hui Zhou, +2

Cancer Management and Research

Quercetin inhibits kidney fibrosis and the epithelial to mesenchymal transition of the renal tubular system involving suppression of the Sonic Hedgehog signaling pathway

Xianghua Liu, Ning Sun, Nan Mo, +4

Food & Function

Apigenin-oxymatrine binary co-amorphous mixture: Enhanced solubility, bioavailability, and anti-inflammatory effect

Bin Li, Yi Hu, Ting Wu, +4

Food Chemistry

Medicinal ChemistryPharmaceutical ScienceActive IngredientPharmacologyEnhanced Solubility +2

HDAC11 deletion reduces fructose-induced cardiac dyslipidemia, apoptosis and inflammation by attenuating oxidative stress injury

Xiaodi Fan, Lanlan Wan, Man Duan, +1

Biochemical and Biophysical Research Communications

InflammationMetabolic SyndromeOxysterolCardiovascular DiseaseBiochemistry +11

Pramipexole nanocrystals for transdermal permeation: Characterization and its enhancement micro-mechanism

Ying Li, Danqing Wang, Shan Lu, +4

European Journal of Pharmaceutical Sciences

Materials ScienceNanomedicineEngineeringNanoscale ChemistryNanomaterials +2

Identification of critical genes associated with human osteosarcoma metastasis based on integrated gene expression profiling

Hongwu Fan, Shan Lu, Shengqun Wang

Molecular Medicine Reports

EngineeringOsteosarcoma DevelopmentPathologyCancer BiologyGene Expression Profiling +23

Coamorphous System of Florfenicol-Oxymatrine for Improving the Solubility and Dissolution Rate of Florfenicol: Preparation, Characterization and Molecular Dynamics Simulation

Bin Li, Yi Hu, Yüjie Guo, +5

Journal of Pharmaceutical Sciences

EngineeringDissolution RateBiochemistrySeparation ScienceNatural Sciences +7