<i>Scutellaria baicalensis</i> extract and baicalein inhibit replication of SARS-CoV-2 and its 3C-like protease <i>in vitro</i>

Hongbo Liu, Fei Ye, Qi Sun, +7

Journal of Enzyme Inhibition and Medicinal Chemistry

Roles of meteorological conditions in COVID-19 transmission on a worldwide scale

Biqing Chen, Hao Liang, Xiaomin Yuan, +6

Worldwide ScaleVirus EpidemiologyEpidemiological DynamicAir TemperatureCovid-19 Epidemiology +18

Potent inhibitors of SARS-CoV-2 3C-like protease derived from N-substituted isatin compounds

Pei Liu, Hongbo Liu, Qi Sun, +5

European Journal of Medicinal Chemistry

N-substituted Isatin CompoundsMedicineAntiviral Drug DevelopmentSars-cov-2 3C-like ProteasePotent Inhibitors +5

A novel mutation in the TUBB8 gene is associated with complete cleavage failure in fertilized eggs

Ping Yuan, Lingyan Zheng, Hao Liang, +6

Journal of Assisted Reproduction and Genetics

BiologyTubb8 GeneComplete Cleavage FailureNovel MutationGenetic Disorder +9

Bardoxolone and bardoxolone methyl, two Nrf2 activators in clinical trials, inhibit SARS-CoV-2 replication and its 3C-like protease

Qi Sun, Fei Ye, Hao Liang, +7

Signal Transduction and Targeted Therapy

3C-like ProteaseBardoxolone MethylMedicineImmunologyClinical Trials +5

<i>Scutellaria baicalensis</i> extract and baicalein inhibit replication of SARS-CoV-2 and its 3C-like protease <i>in vitro</i>

Hongbo Liu, Fei Ye, Qi Sun, +6

Expanding the phenotypic and genetic spectrum of Chinese patients with congenital absence of vas deferens bearing <i><scp>CFTR</scp></i> and <i><scp>ADGRG</scp>2</i> alleles

Ping Yuan, Zuobing Liang, Hao Liang, +10

Andrology

Herb-target interaction network analysis helps to disclose molecular mechanism of traditional Chinese medicine

Hao Liang, Hao Ruan, Qi Ouyang, +1

Scientific Reports

Sequencing of the MHC region defines HLA-DQA1 as the major genetic risk for seropositive rheumatoid arthritis in Han Chinese population

Jianping Guo, Tao Zhang, Hongzhi Cao, +32

Annals of the Rheumatic Diseases

Efficient ligand discovery from natural herbs by integrating virtual screening, affinity mass spectrometry and targeted metabolomics

Zhihua Wang, Hao Liang, Haijie Cao, +8

The Analyst

Drug TargetHit IdentificationMetabolomic ProfilingAntiviral DrugAffinity Mass Spectrometry +15