Chitosan oligosaccharides inhibit LPS-induced over-expression of IL-6 and TNF-α in RAW264.7 macrophage cells through blockade of mitogen-activated protein kinase (MAPK) and PI3K/Akt signaling pathways

Pan Ma, Hongtao Liu, Peng Wei, +4

Carbohydrate Polymers

InflammationCytokineRaw264.7 Macrophage CellsMitogen-activated Protein KinaseImmune Regulation +9

Roles of N-Acetylglucosaminyltransferase III in Epithelial-to-Mesenchymal Transition Induced by Transforming Growth Factor β1 (TGF-β1) in Epithelial Cell Lines

Qingsong Xu, Tomoya Isaji, Yingying Lu, +5

Journal of Biological Chemistry

The inhibition of LPS-induced inflammation in RAW264.7 macrophages via the PI3K/Akt pathway by highly N-acetylated chitooligosaccharide

Qingsong Xu, Meisi Liu, Qishun Liu, +3

Carbohydrate Polymers

InflammationCytokineAnti-inflammatorySignal TransductionLps-induced Inflammation +12

Crustacean hyperglycemic hormones directly modulate the immune response of hemocytes in shrimp Litopenaeus vannamei

Lin Wang, Hao Chen, Jianchao Xu, +5

Fish & Shellfish Immunology

BiologyShrimp Litopenaeus VannameiCrustacean Hyperglycemic HormonesAquaculturePhysiology +6

A novel effector caspase (Caspase-3/7-1) involved in the regulation of immune homeostasis in Chinese mitten crab Eriocheir sinensis

Chen Qu, Wen Yang, Qingsong Xu, +7

Fish & Shellfish Immunology

Signal TransductionAutoimmune DiseaseImmune HomeostasisImmunologyImmune Regulation +9

An inhibitor of apoptosis protein (EsIAP1) from Chinese mitten crab Eriocheir sinensis regulates apoptosis through inhibiting the activity of EsCaspase-3/7-1

Chen Qu, Jiejie Sun, Qingsong Xu, +8

Scientific Reports

The involvement of suppressor of cytokine signaling 6 (SOCS6) in immune response of Chinese mitten crab Eriocheir sinensis

Chen Qu, Qingsong Xu, Mengmeng Lu, +6

Fish & Shellfish Immunology

InflammationCytokineChinese MittenAllergyAutoimmune Disease +10

Beclin-1 is involved in the regulation of antimicrobial peptides expression in Chinese mitten crab Eriocheir sinensis

Wen Yang, Chao Liu, Qingsong Xu, +8

Fish & Shellfish Immunology

Antimicrobial Peptides ExpressionBiochemistryPeptide LibraryImmunologyPeptide Therapeutic +3

Chitosan oligosaccharide inhibits EGF-induced cell growth possibly through blockade of epidermal growth factor receptor/mitogen-activated protein kinase pathway

Qingsong Xu, Wenjing Wang, Wen Yang, +2

International Journal of Biological Macromolecules

Signal TransductionReceptor Tyrosine KinaseImmunologyCell-matrix InteractionCell Proliferation +7

Synthesis of acylated derivatives of chitosan oligosaccharide and evaluation of their potential antifungal agents on Fusarium oxysporum

Bing Li, Lingyu Han, Jinlong Ma, +6

Carbohydrate Polymers

Antifungal AgentFusarium OxysporumAcylated DerivativesChitosan OligosaccharidePolysaccharide +2