John J. Lee

Secretion and localized transcription suggest a role in positional signaling for products of the segmentation gene hedgehog

John J. Lee, Doris P. von Kessler, Suki Parks et al. · Cell · 1992 · 585 citations

Cell Lineage, Developmental Biology, Signaling Pathway +7

Itraconazole, a Commonly Used Antifungal that Inhibits Hedgehog Pathway Activity and Cancer Growth

James Kim, Jean Y. Tang, Ruoyu Gong et al. · Cancer Cell · 2010 · 506 citations · Full text

Antifungal Agent, Antifungal Agents, Medicine +6

The product of hedgehog autoproteolytic cleavage active in local and long-range signalling

Jeffery A. Porter, Doris P. von Kessler, Stephen C. Ekker et al. · Nature · 1995 · 499 citations

Hedgehog Autoproteolytic Cleavage, Protein Function, Developmental Biology +8

Stromal response to Hedgehog signaling restrains pancreatic cancer progression

John J. Lee, Rushika M. Perera, Huaijun Wang et al. · Proceedings of the National Academy of Sciences · 2014 · 490 citations · Full text

Arsenic antagonizes the Hedgehog pathway by preventing ciliary accumulation and reducing stability of the Gli2 transcriptional effector

John J. Lee, James Kim, Dale R. Gardner et al. · Proceedings of the National Academy of Sciences · 2010 · 298 citations · Full text