SIRT1 agonism modulates cardiac NLRP3 inflammasome through pyruvate dehydrogenase during ischemia and reperfusion

Ying Han, Weiju Sun, Di Ren, +6

Redox Biology

CAUSEL: an epigenome- and genome-editing pipeline for establishing function of noncoding GWAS variants

Sándor Spisák, Kate Lawrenson, Yanfang Fu, +16

Nature Medicine

Genome-wide Association StudyAllelic VariantGenome-editing PipelineGeneticsStatistical Genetics +9

Testosterone replacement therapy promotes angiogenesis after acute myocardial infarction by enhancing expression of cytokines HIF-1a, SDF-1a and VEGF

Yeping Chen, Lu Fu, Ying Han, +4

European Journal of Pharmacology

InflammationAngiogenesisCardiovascular DiseaseMyocardial InfarctionImmunology +8

Testosterone improves cardiac function and alters angiotensin II receptors in isoproterenol-induced heart failure

Ningning Kang, Lu Fu, Jin Xu, +4

Archives of cardiovascular diseases

Ii ReceptorsMolecular PharmacologyCardiac FunctionHeart FailureCardiovascular Disease +9

Integration of multiethnic fine-mapping and genomic annotation to prioritize candidate functional SNPs at prostate cancer susceptibility regions

Ying Han, Dennis J. Hazelett, Fredrik Wiklund, +85

Human Molecular Genetics

Testosterone modulation of cardiac β-adrenergic signals in a rat model of heart failure

Junfeng Sun, Lu Fu, Xianling Tang, +5

General and Comparative Endocrinology

Heart FailureEndocrine MechanismHormonal ReceptorPhysiologyNeuroendocrine Mechanism +5

Dammarane-Type Saponins from <i>Gynostemma pentaphyllum</i> Prevent Hypoxia-Induced Neural Injury through Activation of ERK, Akt, and CREB Pathways

Jun Wang, Ming Zhao, Xiang Cheng, +5

Journal of Agricultural and Food Chemistry

LDL-C plays a causal role on T2DM: a Mendelian randomization analysis

Wenbin Pan, Weiju Sun, Shuo Yang, +5

Aging

Identification of epigenetic factor KAT2B gene variants for possible roles in congenital heart diseases

Yongsheng Hou, Jingzhi Wang, Shuai Shi, +7

Bioscience Reports

GeneticsGenetic EpidemiologyMolecular GeneticsGenomicsCongenital Heart Anomaly +26

Reverse strand-displacement amplification strategy for rapid detection of p53 gene

Lisha Wang, Ying Han, Shuai Xiao, +9

Talanta

Molecular Biological MethodNatural SciencesDna AnalysisMolecular BiologyDna Replication +5