Premranjan Kumar

Glycine and N‐acetylcysteine (GlyNAC) supplementation in older adults improves glutathione deficiency, oxidative stress, mitochondrial dysfunction, inflammation, insulin resistance, endothelial dysfunction, genotoxicity, muscle strength, and cognition: Results of a pilot clinical trial

Premranjan Kumar, Chun Liu, Jean W. Hsu et al. · Clinical and Translational Medicine · 2021 · 154 citations · Full text

Supplementing Glycine and N-Acetylcysteine (GlyNAC) in Older Adults Improves Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Physical Function, and Aging Hallmarks: A Randomized Clinical Trial

Premranjan Kumar, Chun Liu, James Suliburk et al. · The Journals of Gerontology Series A · 2022 · 129 citations · Full text

Severe Glutathione Deficiency, Oxidative Stress and Oxidant Damage in Adults Hospitalized with COVID-19: Implications for GlyNAC (Glycine and N-Acetylcysteine) Supplementation

Premranjan Kumar, Ob Osahon, David B. Vides et al. · Antioxidants · 2021 · 88 citations · Full text

GlyNAC (Glycine and N-Acetylcysteine) Supplementation in Mice Increases Length of Life by Correcting Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Abnormalities in Mitophagy and Nutrient Sensing, and Genomic Damage

Premranjan Kumar, Ob Osahon, Rajagopal V. Sekhar · Nutrients · 2022 · 78 citations · Full text

Anti-aging, Aging, Mitochondrial Dysfunction +20

Hyperglycemia-Induced Oxidative-Nitrosative Stress Induces Inflammation and Neurodegeneration via Augmented Tuberous Sclerosis Complex-2 (TSC-2) Activation in Neuronal Cells

Premranjan Kumar, Thiagarajan Raman, Mitali Madhusmita Swain et al. · Molecular Neurobiology · 2016 · 74 citations

Inflammation, Metabolic Syndrome, Neurodegenerative Diseases +12