Theabrownin from Pu-erh tea attenuates hypercholesterolemia via modulation of gut microbiota and bile acid metabolism

Fengjie Huang, Xiaojiao Zheng, Xiaohui Ma, +24

Nature Communications

Bile acid is a significant host factor shaping the gut microbiome of diet-induced obese mice

Xiaojiao Zheng, Fengjie Huang, Aihua Zhao, +9

BMC Biology

Dysregulated hepatic bile acids collaboratively promote liver carcinogenesis

Guoxiang Xie, Xiaoning Wang, Fengjie Huang, +11

International Journal of Cancer

A dysregulated bile acid-gut microbiota axis contributes to obesity susceptibility

Meilin Wei, Fengjie Huang, Ling Zhao, +13

EBioMedicine

Branched-chain and aromatic amino acid profiles and diabetes risk in Chinese populations

Tianlu Chen, Yan Ni, Xiaojing Ma, +8

Scientific Reports

A Clostridia-rich microbiota enhances bile acid excretion in diarrhea-predominant irritable bowel syndrome

Ling Zhao, Wei Yang, Yang Chen, +25

Journal of Clinical Investigation

DysbiosisGastroenterologyIleal Fgf19 ExpressionDigestive TractProbiotics +15

Plasma Metabolite Profiles of Alzheimer’s Disease and Mild Cognitive Impairment

Gang Wang, Yi Zhou, Fengjie Huang, +12

Journal of Proteome Research

Ad PatientsMetabolomic ProfilingNeurochemical BiomarkersAlzheimer's DiseaseClinical Diagnosis +14

Serum Bile Acids Are Associated with Pathological Progression of Hepatitis B-Induced Cirrhosis

Xiaoning Wang, Guoxiang Xie, Aihua Zhao, +6

Journal of Proteome Research

ImmunologyGastroenterologyPathologyHepatitis BLiver Function +22

Conjugated secondary 12α-hydroxylated bile acids promote liver fibrogenesis

Guoxiang Xie, Runqiu Jiang, Xiaoning Wang, +14

EBioMedicine

Sinomenine activation of Nrf2 signaling prevents hyperactive inflammation and kidney injury in a mouse model of obstructive nephropathy

Tian Qin, Ronghui Du, Fengjie Huang, +4

Free Radical Biology and Medicine

InflammationKidney InjuryRenal FunctionMedicineRenal Pathology +12