AAV capsid variants with brain-wide transgene expression and decreased liver targeting after intravenous delivery in mouse and marmoset

David Goertsen, Nicholas C. Flytzanis, Nick Goeden, +13

Nature Neuroscience

HepatologyLiver PhysiologyImmunologyAav Capsid VariantsPathology +6

Imprinted X inactivation maintained by a mouse Polycomb group gene

Jianbo Wang, Jesse Mager, Yijing Chen, +4

Nature Genetics

Knockout MouseChromatinX InactivationGeneticsMolecular Genetics +7

Identification of two bone morphogenetic protein type I receptors in Drosophila and evidence that Brk25D is a decapentaplegic receptor

Andrea Penton, Yijing Chen, Karen Staehling-Hampton, +6

Cell

Developmental BiologySignal TransductionBone Morphogenic ProteinDevelopmental GeneticsGenetics +7

Intrinsic Subtype Switching and Acquired <i>ERBB2</i>/<i>HER2</i> Amplifications and Mutations in Breast Cancer Brain Metastases

Nolan Priedigkeit, Ryan J. Hartmaier, Yijing Chen, +15

JAMA Oncology

Genotype-based screen for ENU-induced mutations in mouse embryonic stem cells

Yijing Chen, Della Yee, Katherine M. Dains, +6

Nature Genetics

Knockout MouseGenotype-based ScreenDevelopmental BiologySomatic VariantCell Specialization +5

Gut Microbiome Alterations Precede Cerebral Amyloidosis and Microglial Pathology in a Mouse Model of Alzheimer’s Disease

Yijing Chen, Lihua Fang, Shuo Chen, +8

BioMed Research International

decapentaplegicOverexpression AffectsDrosophilaWing and Leg Imaginal Disc Development andwinglessExpression

Shigeru Morimura, Lisa Maves, Yijing Chen, +1

Developmental Biology

Developmental BiologyIntervertebral DiscMorphogenesisDecapentaplegicoverexpression AffectsdrosophilawingMedicine

Fibroblast Growth Factor-2 Decreases Metabolic Coupling and Stimulates Phosphorylation as Well as Masking of Connexin43 Epitopes in Cardiac Myocytes

Bradley W. Doble, Yijing Chen, Denis G. Bosc, +2

Circulation Research

Label-free and Dye-free Fluorescent Sensing of Tetracyclines Using a Capture-Selected DNA Aptamer

Yichen Zhao, Steven Ong, Yijing Chen, +2

Analytical Chemistry

Capture-selected Dna AptamerEngineeringMolecular BiologyDye-free Fluorescent SensingDrug Resistance +15

Genomic and transcriptomic investigations of the evolutionary transition from oviparity to viviparity

Wei Gao, Yanbo Sun, Weiwei Zhou, +19

Proceedings of the National Academy of Sciences