A donor-DNA-free CRISPR/Cas-based approach to gene knock-up in rice

Yu Lu, Jiyao Wang, Bo Chen, +24

Nature Plants

EngineeringGeneticsSynthetic BiologyGenetic EngineeringMolecular Biology +7

Paraoxonase 2 decreases renal reactive oxygen species production, lowers blood pressure, and mediates dopamine D2 receptor-induced inhibition of NADPH oxidase

Yu Yang, Yanrong Zhang, Santiago Cuevas, +8

Free Radical Biology and Medicine

Redox SignalingHypertensionRenal FunctionNadph OxidaseMedicine +9

Deficient Dopamine D2 Receptor Function Causes Renal Inflammation Independently of High Blood Pressure

Yanrong Zhang, Santiago Cuevas, Laureano D. Asico, +9

PLoS ONE

HypertensionHigh Blood PressureImmunologyRenal InflammationBlood Pressure +16

Renal rescue of dopamine D2 receptor function reverses renal injury and high blood pressure

Prasad Konkalmatt, Laureano D. Asico, Yanrong Zhang, +6

JCI Insight

Dopamine D2 receptor modulates Wnt expression and control of cell proliferation

Fei Han, Prasad Konkalmatt, Chaitanya S. Mokashi, +13

Scientific Reports

Differential dopamine receptor subtype regulation of adenylyl cyclases in lipid rafts in human embryonic kidney and renal proximal tubule cells

Peiying Yu, Min Sun, Van Anthony M. Villar, +4

Cellular Signalling

Molecular PharmacologySignal TransductionMolecular PhysiologyLipid RaftsFunctional Selectivity +13

A new class of β-carboline alkaloid-peptide conjugates with therapeutic efficacy in acute limb ischemia/reperfusion injury

Wei Bi, Yue Bi, Ping Xue, +8

European Journal of Medicinal Chemistry

β-Carboline Alkaloid-peptide ConjugatesMedicineTherapeutic EfficacyVascular BiologyPharmacotherapy +6

Analyses of long non-coding RNA and mRNA profiles in right ventricle myocardium of acute right heart failure in pulmonary arterial hypertension rats

Yanan Cao, Yue Yang, Lu Wang, +8

Biomedicine & Pharmacotherapy

Cardiac MuscleCardiomyopathyHeart FailurePulmonary Arterial HypertensionCardiovascular Disease +8

Novel TEMPO-PEG-RGDs Conjugates Remediate Tissue Damage Induced by Acute Limb Ischemia/Reperfusion

Wei Bi, Xiaoxu Li, Yue Bi, +7

Journal of Medicinal Chemistry

Acute Limb Ischemia/reperfusionLipid PeroxidationImmunologyPharmacotherapyBiomedical Engineering +19

Indole-TEMPO conjugates alleviate ischemia-reperfusion injury via attenuation of oxidative stress and preservation of mitochondrial function

Wei Bi, Yue Bi, Xiang Gao, +8

Bioorganic & Medicinal Chemistry

InflammationMitochondrial FunctionBiochemistryMedicineReperfusion Injury +9