Siwei Li

Discovery of QCA570 as an Exceptionally Potent and Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of the Bromodomain and Extra-Terminal (BET) Proteins Capable of Inducing Complete and Durable Tumor Regression

Chong Qin, Yang Hu, Bing Zhou et al. · Journal of Medicinal Chemistry · 2018 · 258 citations · Full text

Molecular Biology, Bet Proteins, Bet Inhibitors +22

PLC-γ1 and Rac1 Coregulate EGF-Induced Cytoskeleton Remodeling and Cell Migration

Siwei Li, Qian Wang, Yi Wang et al. · Molecular Endocrinology · 2009 · 101 citations · Full text

Epidermal Growth Factor, Cytoskeleton, Cell Growth +16

TRIM11 facilitates chemoresistance in nasopharyngeal carcinoma by activating the β-catenin/ABCC9 axis via p62-selective autophagic degradation of Daple

Runa Zhang, Siwei Li, Lijuan Liu et al. · Oncogenesis · 2020 · 92 citations · Full text

Structure-Based Optimization of a Novel Class of Aldehyde Dehydrogenase 1A (ALDH1A) Subfamily-Selective Inhibitors as Potential Adjuncts to Ovarian Cancer Chemotherapy

Brandt C. Huddle, Edward Grimley, Cameron D. Buchman et al. · Journal of Medicinal Chemistry · 2018 · 67 citations · Full text

Measurement of <i>in vivo</i> Gastrointestinal Release and Dissolution of Three Locally Acting Mesalamine Formulations in Regions of the Human Gastrointestinal Tract

Alex Yu, Jason Baker, Ann Fioritto et al. · Molecular Pharmaceutics · 2016 · 52 citations