Protein arginine methyltransferase 5 is essential for growth of lung cancer cells

Zhongping Gu, Shen Gao, Fahao Zhang, +4

Biochemical Journal

Prmt5 ExpressionTumor MicroenvironmentCell SignalingMedicineCancer Growth +12

Protein Arginine Methyltransferase 5 Functions in Opposite Ways in the Cytoplasm and Nucleus of Prostate Cancer Cells

Zhongping Gu, Yirong Li, Peng Lee, +3

PLoS ONE

Epigenetic ChangeMolecular BiologyProstate Cancer CellsEpigeneticsTumor Biology +14

Protein arginine methyltransferase 5 promotes lung cancer metastasis via the epigenetic regulation of miR-99 family/FGFR3 signaling

Pengyu Jing, Nan Zhao, Mingxiang Ye, +6

Cancer Letters

Lung Cancer ProgressionTumor MicroenvironmentMedicineEpigenetic ChangeArginine Residues +12

Upregulated fascin1 in non-small cell lung cancer promotes the migration and invasiveness, but not proliferation

Jinbo Zhao, Yongan Zhou, Zhipei Zhang, +5

Cancer Letters

MedicineAutophagyPathologyCancer BiologyLung Cancer +5

A miR-124/ITGA3 axis contributes to colorectal cancer metastasis by regulating anoikis susceptibility

Ke-di Sa, Xiang Zhang, Xiaofei Li, +5

Biochemical and Biophysical Research Communications

Anoikis SusceptibilityMir-124/itga3 Axis ContributesMedicineColorectal CancerPathology +10

VEGF₁₆₅antisense RNA suppresses oncogenic properties of human esophageal squamous cell carcinoma

Zhongping Gu

World Journal of Gastroenterology

Enhancement of Radiosensitivity by Roscovitine Pretreatment in Human Non-small Cell Lung Cancer A549 Cells

Feng Zhang, Tao Zhang, Zhongping Gu, +6

Journal of Radiation Research

Radiation MedicineRadiation TherapyMedicinePharmacologyKu80 Proteins +13

miR-24-3p/FGFR3 Signaling as a Novel Axis Is Involved in Epithelial-Mesenchymal Transition and Regulates Lung Adenocarcinoma Progression

Pengyu Jing, Nan Zhao, Nianlin Xie, +7

Journal of Immunology Research

Selective small-chemical inhibitors of protein arginine methyltransferase 5 with anti-lung cancer activity

Guimei Kong, Min Yu, Zhongping Gu, +4

PLoS ONE

Lead CompoundsDrug TargetChemoprevention StrategyTumor BiologyMolecular Pharmacology +18

Wortmannin potentiates roscovitine-induced growth inhibition in human solid tumor cells by repressing PI3K/Akt pathway

Feng Zhang, Tao Zhang, Tao Jiang, +5

Cancer Letters

OncologyRoscovitine-induced Growth InhibitionOncogenic AgentMedicineCancer Biology +7