Yongzheng Zhang

Discovery of Brivanib Alaninate ((<i>S</i>)-((<i>R</i>)-1-(4-(4-Fluoro-2-methyl-1<i>H</i>-indol-5-yloxy)-5-methylpyrrolo[2,1-<i>f</i>][1,2,4]triazin-6-yloxy)propan-2-yl)2-aminopropanoate), A Novel Prodrug of Dual Vascular Endothelial Growth Factor Receptor-2 and Fibroblast Growth Factor Receptor-1 Kinase Inhibitor (BMS-540215)

Zhen‐Wei Cai, Yongzheng Zhang, R. M. Borzilleri et al. · Journal of Medicinal Chemistry · 2008 · 141 citations · Full text

Pharmaceutical Science, Oral Bioavailability, L-alanine Prodrug 8 +20

Pharmacokinetics and in vivo antistaphylococcal efficacy of TXY541, a 1-methylpiperidine-4-carboxamide prodrug of PC190723

Malvika Kaul, Lilly Mark, Yongzheng Zhang et al. · Biochemical Pharmacology · 2013 · 46 citations

Pharmacology, Clinical Pharmacology, Pharmacotherapy +5

Catalpol alleviates ovalbumin-induced asthma in mice: Reduced eosinophil infiltration in the lung

Yanyan Chen, Yongzheng Zhang, Mingyuan Xu et al. · International Immunopharmacology · 2016 · 40 citations

Asthma, Inflammation, Anti-inflammatory +10

Inhibition of RND-type efflux pumps confers the FtsZ-directed prodrug TXY436 with activity against Gram-negative bacteria

Malvika Kaul, Yongzheng Zhang, Ajit K. Parhi et al. · Biochemical Pharmacology · 2014 · 35 citations

Antimicrobial Drug Discovery, Antibiotics, Ftsz-directed Prodrug Txy436 +10

Enterococcal and streptococcal resistance to PC190723 and related compounds: Molecular insights from a FtsZ mutational analysis

Malvika Kaul, Yongzheng Zhang, Ajit K. Parhi et al. · Biochimie · 2013 · 26 citations · Full text

Antimicrobial Resistance Gene, Health Sciences, Streptococcal Resistance +11