The genome and transcriptome of Japanese flounder provide insights into flatfish asymmetry

Changwei Shao, Baolong Bao, Zhiyuan Xie, +32

Nature Genetics

Recombinant CC16 inhibits NLRP3/caspase-1-induced pyroptosis through p38 MAPK and ERK signaling pathways in the brain of a neonatal rat model with sepsis

Ruixi Zhou, Xiaoyan Yang, Xihong Li, +4

Journal of Neuroinflammation

Chromosome-level genome assembly of the spotted sea bass, <i>Lateolabrax maculatus</i>

Changwei Shao, Chang Li, Na Wang, +11

GigaScience

Involvement of the JNK/FOXO3a/Bim Pathway in Neuronal Apoptosis after Hypoxic–Ischemic Brain Damage in Neonatal Rats

Deyuan Li, Xihong Li, Jinlin Wu, +6

PLoS ONE

Jnk InhibitionApoptosisCell DeathJnk/foxo3a/bim PathwayTumor Biology +22

A new anti-lipopolysaccharide factor isoform (PtALF4) from the swimming crab Portunus trituberculatus exhibited structural and functional diversity of ALFs

Yuan Liu, Zhaoxia Cui, Xihong Li, +3

Fish & Shellfish Immunology

BiosynthesisBiochemistryFunctional DiversityCrab Portunus TrituberculatusMicrobiology

Comparative transcriptomic analysis provides insights into the molecular basis of brachyurization and adaptation to benthic lifestyle in Eriocheir sinensis

Chengwen Song, Zhaoxia Cui, Min Hui, +3

Gene

BiologyBenthic CommunityPhylogeneticsMolecular EcologyIntegrative Biology +9

A newly identified anti-lipopolysaccharide factor from the swimming crab Portunus trituberculatus with broad spectrum antimicrobial activity

Yuan Liu, Zhaoxia Cui, Xihong Li, +2

Fish & Shellfish Immunology

Anti-lipopolysaccharide FactorHealth SciencesMedicineCrab Portunus TrituberculatusAntibacterial Agent +7

The ligand-gated ion channel P2X7 receptor mediates NLRP3/caspase-1-mediated pyroptosis in cerebral cortical neurons of juvenile rats with sepsis

Xuemei Sun, Ruixi Zhou, Yupeng Lei, +2

Brain Research

Sepsis-associated EncephalopathySevere SepsisApoptosisImmunologyCell Death +23

MicroRNA‑93 contributes to the suppression of lung inflammatory responses in LPS‑induced acute lung injury in mice via the TLR4/MyD88/NF‑κB signaling pathway

Hu Gao, Dongqiong Xiao, Linbo Gao, +1

International Journal of Molecular Medicine

Acute Lung InjuryInflammatory Lung DiseaseLung InflammationInnate Immune SystemImmunology +15

Comparative transcriptome profiling of immune response against Vibrio harveyi infection in Chinese tongue sole

Hao Xu, Xiwen Xu, Xihong Li, +4

Scientific Data

Fatal VibriosisComparative Transcriptome ProfilingMedicineVirulence FactorPathogenesis +12