Sirui Li

STING-induced regulatory B cells compromise NK function in cancer immunity

Sirui Li, Bhalchandra Mirlekar, Brandon M. Johnson et al. · Nature · 2022 · 282 citations · Full text

Cancer Immunosurveillance, Cancer Immunity, Immunology +6

Zinc cyclic di-AMP nanoparticles target and suppress tumours via endothelial STING activation and tumour-associated macrophage reinvigoration

Kaiting Yang, Wenbo Han, Xiaomin Jiang et al. · Nature Nanotechnology · 2022 · 186 citations

Nanoparticles, Nanomedicine, Suppress Tumours +11

Intratumoral Delivery of IL-21 Overcomes Anti-Her2/Neu Resistance through Shifting Tumor-Associated Macrophages from M2 to M1 Phenotype

Meng Xu, Mingyue Liu, Xuexiang Du et al. · The Journal of Immunology · 2015 · 139 citations

Tumor-associated Macrophages, Intratumoral Delivery, Breast Oncology +19

mRNA Delivery of a Bispecific Single‐Domain Antibody to Polarize Tumor‐Associated Macrophages and Synergize Immunotherapy against Liver Malignancies

Ying Wang, Karthik Tiruthani, Sirui Li et al. · Advanced Materials · 2021 · 127 citations · Full text

UBE2M-mediated neddylation of TRIM21 regulates obesity-induced inflammation and metabolic disorders

Xinliang Lu, Xianghui Kong, Hao Wu et al. · Cell Metabolism · 2023 · 103 citations · Full text

Metabolic Syndrome, Ube2m-mediated Neddylation, Signal Transduction +10