Xuexiang Du

A reappraisal of CTLA-4 checkpoint blockade in cancer immunotherapy

Xuexiang Du, Fei Tang, Mingyue Liu et al. · Cell Research · 2018 · 236 citations · Full text

Intratumoral Delivery of IL-21 Overcomes Anti-Her2/Neu Resistance through Shifting Tumor-Associated Macrophages from M2 to M1 Phenotype

Meng Xu, Mingyue Liu, Xuexiang Du et al. · The Journal of Immunology · 2015 · 139 citations

Tumor-associated Macrophages, Intratumoral Delivery, Breast Oncology +19

Uncoupling therapeutic from immunotherapy-related adverse effects for safer and effective anti-CTLA-4 antibodies in CTLA4 humanized mice

Xuexiang Du, Mingyue Liu, Juanjuan Su et al. · Cell Research · 2018 · 128 citations · Full text

T-regulatory Cell, Immunology, Immune Regulation +22

Targeting HIF-1α abrogates PD-L1–mediated immune evasion in tumor microenvironment but promotes tolerance in normal tissues

Christopher M. Bailey, Yan Liu, Mingyue Liu et al. · Journal of Clinical Investigation · 2022 · 124 citations · Full text

Hijacking antibody-induced CTLA-4 lysosomal degradation for safer and more effective cancer immunotherapy

Yan Zhang, Xuexiang Du, Mingyue Liu et al. · Cell Research · 2019 · 122 citations · Full text