HOTTIP lncRNA Promotes Hematopoietic Stem Cell Self-Renewal Leading to AML-like Disease in Mice

Huacheng Luo, Ganqian Zhu, Jianfeng Xu, +16

Cancer Cell

Developmental BiologyAml-like DiseaseMedicineHematologyStem Cell Research +6

Gain of function of ASXL1 truncating protein in the pathogenesis of myeloid malignancies

Hui Yang, Stefan Kurtenbach, Ying Guo, +18

Blood

Parallel ddRAD and Genome Skimming Analyses Reveal a Radiative and Reticulate Evolutionary History of the Temperate Bamboos

Cen Guo, Pengfei Ma, Guoqian Yang, +6

Systematic Biology

Temperate BamboosComparative GenomicsGeneticsGenomicsDdrad Data +20

HOXBLINC long non-coding RNA activation promotes leukemogenesis in NPM1-mutant acute myeloid leukemia

Ganqian Zhu, Huacheng Luo, Yang Feng, +18

Nature Communications

A signalling pathway for transcriptional regulation of sleep amount in mice

Rui Zhou, Guodong Wang, Qi Li, +26

Nature

Transcriptional RegulationSystems BiologyDevelopmental BiologySignal TransductionSleep +9

ASXL1 interacts with the cohesin complex to maintain chromatid separation and gene expression for normal hematopoiesis

Zhaomin Li, Peng Zhang, Aimin Yan, +19

Science Advances

Loss of ASXL1 in the bone marrow niche dysregulates hematopoietic stem and progenitor cell fates

Peng Zhang, Zizhen Chen, Rong Li, +14

Cell Discovery

Reactive oxygen species, but not mitochondrial membrane potential, is associated with radiation‐induced apoptosis of AHH‐1 human lymphoblastoid cells

Zi‐Bing Wang, Yuqing Liu, Ying Zhang, +7

Cell Biology International

Loss of Asxl2 leads to myeloid malignancies in mice

Jianping Li, Fuhong He, Peng Zhang, +20

Nature Communications

Chromatin regulator Asxl1 loss and Nf1 haploinsufficiency cooperate to accelerate myeloid malignancy

Peng Zhang, Fuhong He, Jie Bai, +14

Journal of Clinical Investigation

Asxl1δ/δ Nf1δ/δ MiceMixed-phenotype Acute LeukemiaImmunologyEpigeneticsTumor Biology +21