Yong Zhang

Decarboxylative alkylation for site-selective bioconjugation of native proteins via oxidation potentials

Steven Bloom, Chun Liu, Dominik K. Kölmel et al. · Nature Chemistry · 2017 · 365 citations · Full text

Aldehyde Dehydrogenase, Oxidation Potentials, Biochemistry +8

Inhibition of Breast Cancer Metastases by a Novel Inhibitor of TGFβ Receptor 1

Yuanzhang Fang, Yihua Chen, Linxi Yu et al. · JNCI Journal of the National Cancer Institute · 2012 · 90 citations · Full text

The mechanism of Fe2+-initiated lipid peroxidation in liposomes: the dual function of ferrous ions, the roles of the pre-existing lipid peroxides and the lipid peroxyl radical

Tang Li-xia, Yong Zhang, Zhong‐Ming Qian et al. · Biochemical Journal · 2000 · 88 citations · Full text

Pre-existing Lipid Peroxides, Fe2+-initiated Lipid Peroxidation, Bioorganic Chemistry +14

The Discovery of Macrocyclic XIAP Antagonists from a DNA-Programmed Chemistry Library, and Their Optimization To Give Lead Compounds with in Vivo Antitumor Activity

Benjamin A. Seigal, William H. Connors, Andrew W. Fraley et al. · Journal of Medicinal Chemistry · 2015 · 85 citations · Full text

Lead Compounds, Molecular Biology, Lead Identification +21

Utilizing Structures of CYP2D6 and BACE1 Complexes To Reduce Risk of Drug–Drug Interactions with a Novel Series of Centrally Efficacious BACE1 Inhibitors

Michael A. Brodney, Elizabeth M. Beck, Christopher R. Butler et al. · Journal of Medicinal Chemistry · 2015 · 78 citations · Full text

Reduce Risk, Drug Target, Peptide Science +21