Tanshinone IIA Attenuates the Inflammatory Response and Apoptosis after Traumatic Injury of the Spinal Cord in Adult Rats

Xin Yin, Yue Yin, Fa-Le Cao, +5

PLoS ONE

SIRT3 deficiency exacerbates p53/Parkin‑mediated mitophagy inhibition and promotes mitochondrial dysfunction: Implication for aged hearts

Yan Li, Ying Ma, Liqiang Song, +6

International Journal of Molecular Medicine

MitophagyAgingMitochondrial DysfunctionMitophagy InhibitionOxidative Stress +19

Metformin mediates cardioprotection against aging‐induced ischemic necroptosis

Chen Li, Nan Mu, Chunhu Gu, +8

Aging Cell

AgingCell DeathAbstract NecroptosisAging‐induced Ischemic NecroptosisBiogerontology +15

TGF-β1-Induced SOX18 Elevation Promotes Hepatocellular Carcinoma Progression and Metastasis Through Transcriptionally Upregulating PD-L1 and CXCL12

Jie Chen, Weibo Feng, Mengyu Sun, +10

Gastroenterology

Melatonin attenuates chronic pain related myocardial ischemic susceptibility through inhibiting RIP3-MLKL/CaMKII dependent necroptosis

Zheng Yang, Chen Li, Yishi Wang, +7

Journal of Molecular and Cellular Cardiology

InflammationHeart FailureHealth SciencesPain MedicineMedicine +8

Metformin promotes autophagy in ischemia/reperfusion myocardium via cytoplasmic AMPKα1 and nuclear AMPKα2 pathways

Yishi Wang, Zheng Yang, Guoxu Zheng, +4

Life Sciences

Cardiac MuscleMitophagyCell AutophagyMolecular PhysiologySignal Transduction +12

Aldehyde dehydrogenase 2 activation in aged heart improves the autophagy by reducing the carbonyl modification on SIRT1

Bing Wu, Lu Yu, Yishi Wang, +7

Oncotarget

Anti-nociceptive effects of Tanshinone IIA (TIIA) in a rat model of complete Freund's adjuvant (CFA)-induced inflammatory pain

Shukai Sun, Yue Yin, Xin Yin, +5

Brain Research Bulletin

InflammationAnti-inflammatoryAllergyInflammatory PainAcute Pain +9

Impaired Cardiac SIRT1 Activity by Carbonyl Stress Contributes to Aging-Related Ischemic Intolerance

Chunhu Gu, Yuan Xing, Li Jiang, +7

PLoS ONE

Metformin-Enhanced Cardiac AMP-Activated Protein Kinase/Atrogin-1 Pathways Inhibit Charged Multivesicular Body Protein 2B Accumulation in Ischemia–Reperfusion Injury

Tian Li, Yue Yin, Nan Mu, +7

Frontiers in Cell and Developmental Biology