Relayed signaling between mesenchymal progenitors and muscle stem cells ensures adaptive stem cell response to increased mechanical load

Akihiro Kaneshige, Takayuki Kaji, Lidan Zhang, +16

Cell stem cell

Muscle HypertrophyEngineeringAdult Stem CellMechanotransductionCellular Physiology +20

Sustained expression of HeyL is critical for the proliferation of muscle stem cells in overloaded muscle

Sumiaki Fukuda, Akihiro Kaneshige, Takayuki Kaji, +10

eLife

The CalcR-PKA-Yap1 Axis Is Critical for Maintaining Quiescence in Muscle Stem Cells

Lidan Zhang, Yu-taro Noguchi, Hiroyuki Nakayama, +10

Cell Reports

Selective inhibition of EZH2 by ZLD1039 blocks H3K27methylation and leads to potent anti-tumor activity in breast cancer

Xuejiao Song, Tiantao Gao, Ningyu Wang, +11

Scientific Reports

Strong, tough and anisotropic bioinspired hydrogels

Shu Wang, Lei Ling, Yuanhao Tian, +12

Materials Horizons

EngineeringBiomimetic MaterialsAnisotropic Pva HydrogelsResponsive PolymersBiomaterials Design +14

Synthesis and structure–activity relationships evaluation of benzothiazinone derivatives as potential anti-tubercular agents

Chao Gao, Tinghong Ye, Ningyu Wang, +10

Bioorganic & Medicinal Chemistry Letters

Potential Anti-tubercular AgentsBenzothiazinone DerivativesMedicinePharmacological AgentPharmacotherapy +4

Cell-autonomous and redundant roles of Hey1 and HeyL in muscle stem cells: HeyL requires Hes1 to bind diverse DNA sites

Yu-taro Noguchi, Miki Nakamura, Nobumasa Hino, +15

Development

Diverse Dna SitesChromatinCell LineageDevelopmental BiologyCell Regulation +13

Discovery and structure–activity relationships study of novel thieno[2,3-b]pyridine analogues as hepatitis C virus inhibitors

Ningyu Wang, Weiqiong Zuo, Ying Xu, +9

Bioorganic & Medicinal Chemistry Letters

MedicineAntiviral Drug DevelopmentRational Drug DesignStructure–activity Relationships StudyChemistry +4

Benzothiazinethione is a potent preclinical candidate for the treatment of drug-resistant tuberculosis

Chao Gao, Cuiting Peng, Xinyu You, +10

Scientific Reports

Synthesis and antitubercular evaluation of 4-carbonyl piperazine substituted 1,3-benzothiazin-4-one derivatives

Cuiting Peng, Chao Gao, Ningyu Wang, +10

Bioorganic & Medicinal Chemistry Letters

Medicinal Chemistry4-Carbonyl PiperazineDerivativesHeterocyclicDerivative (Chemistry) +6