Cross-talk between Epidermal Growth Factor Receptor and Hypoxia-inducible Factor-1α Signal Pathways Increases Resistance to Apoptosis by Up-regulating Survivin Gene Expression

Xianghong Peng, Prasanthi Karna, Zehong Cao, +3

Journal of Biological Chemistry

Leukaemogenic effects of Ptpn11 activating mutations in the stem cell microenvironment

Lei Dong, Wen-Mei Yu, Hong Zheng, +8

Nature

Lineage PlasticityDevelopmental BiologyCell RegulationCell SpecializationMedicine +8

Expression and Regulation of Bcl-2, Bcl-xl, and Bax Correlate With p53 Status and Sensitivity to Apoptosis in Childhood Acute Lymphoblastic Leukemia

Harry W. Findley, Lubing Gu, Andrew M. Yeager, +1

Blood

Regulation of XIAP Translation and Induction by MDM2 following Irradiation

Lubing Gu, Ningxi Zhu, Hongying Zhang, +3

Cancer Cell

Signal TransductionXiap TranslationRadiation EffectRadiation ExposureMolecular Biology +4

DNA Damage Induces a Novel p53-Survivin Signaling Pathway Regulating Cell Cycle and Apoptosis in Acute Lymphoblastic Leukemia Cells

Muxiang Zhou, Lubing Gu, Fengzhi Li, +3

Journal of Pharmacology and Experimental Therapeutics

Degradation of MDM2 by the Interaction between Berberine and DAXX Leads to Potent Apoptosis in MDM2-Overexpressing Cancer Cells

Xiaoling Zhang, Lubing Gu, Jiansha Li, +5

Cancer Research

Chemoprevention StrategyApoptosisImmunologyCell DeathMdm2-overexpressing Cancer Cells +14

MDM2 induces NF-κB/p65 expression transcriptionally through Sp1-binding sites: a novel, p53-independent role of MDM2 in doxorubicin resistance in acute lymphoblastic leukemia

Lubing Gu, Harry W. Findley, Muxiang Zhou

Blood

PTEN reverses MDM2-mediated chemotherapy resistance by interacting with p53 in acute lymphoblastic leukemia cells.

Muxiang Zhou, Lubing Gu, Harry W. Findley, +2

PubMed

ApoptosisImmunologyCell DeathCancer BiologyTumor Biology +16

KLF5 Interacts with p53 in Regulating Survivin Expression in Acute Lymphoblastic Leukemia

Ningxi Zhu, Lubing Gu, Harry W. Findley, +4

Journal of Biological Chemistry

Cancer ResearchKlf5 ProteinCell RegulationMedicineAcute Lymphoblastic Leukemia +10

MDM2 Regulates Vascular Endothelial Growth Factor mRNA Stabilization in Hypoxia

Sheng Zhou, Lubing Gu, Jing He, +2

Molecular and Cellular Biology

Cancer BiologyTumor BiologyOxidative StressAngiogenesisRedox Regulator +16