Chao Zhang

IRE1 Signaling Affects Cell Fate During the Unfolded Protein Response

Jonathan H. Lin, Han Li, Douglas Yasumura et al. · Science · 2007 · 1.4K citations

Apoptosis, Molecular Biology, Cell Death +17

The unfolded protein response signals through high-order assembly of Ire1

Alexei Korennykh, Pascal F. Egea, Janet Finer-Moore et al. · Nature · 2008 · 661 citations · Full text

Protein Function, Biochemistry, Protein Assembly +8

A Circular RNA Binds To and Activates AKT Phosphorylation and Nuclear Localization Reducing Apoptosis and Enhancing Cardiac Repair

Yan Zeng, William W. Du, Yingya Wu et al. · Theranostics · 2017 · 420 citations · Full text

RAF inhibitors that evade paradoxical MAPK pathway activation

Chao Zhang, Wayne Spevak, Ying Zhang et al. · Nature · 2015 · 374 citations

Signaling Pathway, Medicine, Receptor Tyrosine Kinase +5

Chemical genetics reveals the requirement for Polo-like kinase 1 activity in positioning RhoA and triggering cytokinesis in human cells

Mark E. Burkard, Catherine L. Randall, Stéphane Larochelle et al. · Proceedings of the National Academy of Sciences · 2007 · 255 citations · Full text

Chemical Genetics, Signal Transduction, Signaling Pathway +13