Le Li

Asparagine enhances LCK signalling to potentiate CD8+ T-cell activation and anti-tumour responses

Jun Wu, Gen Li, Le Li et al. · Nature Cell Biology · 2021 · 217 citations · Full text

Cancer Immunosurveillance, Receptor Tyrosine Kinase, Cd8+ T-cell Activation +10

p53 regulation of ammonia metabolism through urea cycle controls polyamine biosynthesis

Le Li, Youxiang Mao, Lina Zhao et al. · Nature · 2019 · 187 citations

Biochemistry, Natural Sciences, Ammonia Metabolism +6

p53-mediated control of aspartate-asparagine homeostasis dictates LKB1 activity and modulates cell survival

Longfei Deng, Pengbo Yao, Le Li et al. · Nature Communications · 2020 · 111 citations · Full text

TAp73-induced phosphofructokinase-1 transcription promotes the Warburg effect and enhances cell proliferation

Le Li, Lijia Li, Wěi Li et al. · Nature Communications · 2018 · 93 citations · Full text

Aspartate β-hydroxylase promotes pancreatic ductal adenocarcinoma metastasis through activation of SRC signaling pathway

Kosuke Ogawa, Qiushi Lin, Le Li et al. · Journal of Hematology & Oncology · 2019 · 87 citations · Full text