Replacement of Oct4 by Tet1 during iPSC Induction Reveals an Important Role of DNA Methylation and Hydroxymethylation in Reprogramming

Yawei Gao, Jiayu Chen, Ke Li, +16

Cell stem cell

Important RoleEpigenetic ChangeGeneticsDna MethylationEpigenomics +7

Kidney-derived mesenchymal stem cells contribute to vasculogenesis, angiogenesis and endothelial repair

Jun Chen, Hyeong Cheon Park, Francesco Addabbo, +5

Kidney International

Tissue EngineeringRegenerative MedicineDevelopmental BiologyAngiogenesisMedicine +8

Hierarchical Oct4 Binding in Concert with Primed Epigenetic Rearrangements during Somatic Cell Reprogramming

Jun Chen, Xiaolong Chen, Min Li, +12

Cell Reports

Epigenetic ChangeMolecular BiologyEpigeneticsTranscriptional RegulationCell Reprogramming +18

Fast and robust adjustment of cell mixtures in epigenome-wide association studies with SmartSVA

Jun Chen, Ehsan Behnam, Jinyan Huang, +4

BMC Genomics

Aerosol hygroscopic growth, contributing factors, and impact on haze events in a severely polluted region in northern China

Jun Chen, Zhanqing Li, Min Lv, +7

Atmospheric chemistry and physics

Environmental MonitoringEngineeringUrban Air QualityAir QualityParticulate Matter +14

Methylation Markers for Small Cell Lung Cancer in Peripheral Blood Leukocyte DNA

Liang Wang, Jeremiah A. Aakre, Ruoxiang Jiang, +6

Journal of Thoracic Oncology

ChromatinNucleic Acid BiomarkersMedicineEpigenetic ChangeEpigenomics +9

Kdm6a suppresses the alternative activation of macrophages and impairs energy expenditure in obesity

Jun Chen, Xing Xu, Yan Li, +6

Cell Death and Differentiation

CpG island methylator phenotype involving tumor suppressor genes located on chromosome 3p in non-small cell lung cancer

Zeyi Liu, Jun Zhao, Xiaofeng Chen, +10

Lung Cancer

Chromosome 3PEpigenetic ChangeGeneticsEpigenomicsCancer Genomics +8

A half-Gaussian fitting method for estimating fractional vegetation cover of corn crops using unmanned aerial vehicle images

Linyuan Li, Xihan Mu, Craig Macfarlane, +4

Agricultural and Forest Meteorology

Precision AgricultureEngineeringHalf-gaussian Fitting MethodLand UseCropping System +10

Enhancer Reprogramming within Pre-existing Topologically Associated Domains Promotes TGF-β-Induced EMT and Cancer Metastasis

Yunbo Qiao, Zejian Wang, Fangzhi Tan, +8

Molecular Therapy