InterVar: Clinical Interpretation of Genetic Variants by the 2015 ACMG-AMP Guidelines

Quan Li, Kai Wang

The American Journal of Human Genetics

Genetic VariantsAllelic VariantClinical InterpretationMedicineGenetics +11

Variant Interpretation for Cancer (VIC): a computational tool for assessing clinical impacts of somatic variants

Max M. He, Quan Li, Muqing Yan, +6

Genome Medicine

Single-Cell Analysis Reveals Transcriptomic Features of Drug-Tolerant Persisters and Stromal Adaptation in a Patient-Derived EGFR-Mutated Lung Adenocarcinoma Xenograft Model

Nadeem Moghal, Quan Li, Erin Stewart, +10

Journal of Thoracic Oncology

Integrative analysis of non-small cell lung cancer patient-derived xenografts identifies distinct proteotypes associated with patient outcomes

Shideh Mirhadi, Shirley Tam, Quan Li, +24

Nature Communications

Heme oxygenase-1: a molecular brake on hepatocellular carcinoma cell migration

Cheng Zou, Hong‐Long Zhang, Quan Li, +12

Carcinogenesis

PathologyHeme Oxygenase-1Cancer BiologyRedox BiologyTumor Biology +16

Autoantibodies to Perilipin-1 Define a Subset of Acquired Generalized Lipodystrophy

Caleigh Mandel‐Brehm, Sara E. Vazquez, Christopher S. Liverman, +24

Diabetes

Immune ToleranceImmunologyPathologyImmunotherapyImmunological Biomarkers +17

Identification of histone methyltransferase NSD2 as an important oncogenic gene in colorectal cancer

Lihao Zhao, Quan Li, Zhijun Huang, +5

Cell Death and Disease

Histone ModificationsEpigenetic ChangeGeneticsPathologyCancer Biology +20

BRAF V600E mutation and MET amplification as resistance pathways of the second-generation anaplastic lymphoma kinase (ALK) inhibitor alectinib in lung cancer

Ruoshi Shi, Sebastião N. Martins Filho, Ming Li, +16

Lung Cancer

Braf V600e MutationRadiation OncologyResistance PathwaysMet AmplificationMedicine +7

Outpatient rapid 4-step desensitization for gynecologic oncology patients with mild to low-risk, moderate hypersensitivity reactions to carboplatin/cisplatin

Quan Li, David E. Cohn, Allyson Waller, +5

Gynecologic Oncology

Moderate Hypersensitivity ReactionsMedicineCancer ManagementPharmacologyGynecology +5

Mitapivat increases ATP and decreases oxidative stress and erythrocyte mitochondria retention in a SCD mouse model

Zenaide Quezado, Sayuri Kamimura, Meghann L. Smith, +19

Blood Cells Molecules and Diseases

MitophagyMitochondrial FunctionBiochemistryScd Mouse ModelLipid Peroxidation +9