Pan Chen

Ezh2 phosphorylation state determines its capacity to maintain CD8+ T memory precursors for antitumor immunity

Shan He, Yongnian Liu, Lijun Meng et al. · Nature Communications · 2017 · 131 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

SIRT6 as a key event linking P53 and NRF2 counteracts APAP-induced hepatotoxicity through inhibiting oxidative stress and promoting hepatocyte proliferation

Yanying Zhou, Xiaomei Fan, Tingying Jiao et al. · Acta Pharmaceutica Sinica B · 2020 · 124 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17

Hepato-protective effect of resveratrol against acetaminophen-induced liver injury is associated with inhibition of CYP-mediated bioactivation and regulation of SIRT1–p53 signaling pathways

Ying Wang, Yiming Jiang, Xiaomei Fan et al. · Toxicology Letters · 2015 · 121 citations

Veterinary Medicine, Molecular Medicine, Pharmacology +16

Hepato-protective effects of six schisandra lignans on acetaminophen-induced liver injury are partially associated with the inhibition of CYP-mediated bioactivation

Yiming Jiang, Xiaomei Fan, Ying Wang et al. · Chemico-Biological Interactions · 2015 · 117 citations

Pharmacy, Pharmacology, Toxicology +14

Carnitine palmitoyltransferase 1C regulates cancer cell senescence through mitochondria-associated metabolic reprograming

Yongtao Wang, Yixin Chen, Lihuan Guan et al. · Cell Death and Differentiation · 2018 · 93 citations

Life Sciences, Molecular Biology, Oncology +15