SIRT6 as a key event linking P53 and NRF2 counteracts APAP-induced hepatotoxicity through inhibiting oxidative stress and promoting hepatocyte proliferation

Yanying Zhou, Xiaomei Fan, Tingying Jiao, +10

Acta Pharmaceutica Sinica B

Immune-associated parameters and antioxidative responses to cadmium in the freshwater crab Sinopotamon henanense

Yanying Zhou, Hans‐Uwe Dahms, Feng Dong, +2

Ecotoxicology and Environmental Safety

Antioxidative ResponsesAquaculturePhysiologyImmunologyBioactive Metal +8

p53 attenuates acetaminophen-induced hepatotoxicity by regulating drug-metabolizing enzymes and transporter expression

Jiahong Sun, Yajie Wen, Yanying Zhou, +7

Cell Death and Disease

Dexamethasone-Induced Liver Enlargement Is Related to PXR/YAP Activation and Lipid Accumulation but Not Hepatocyte Proliferation

Tingying Jiao, Xinpeng Yao, Ying-Yuan Zhao, +10

Drug Metabolism and Disposition

Oxidative damages by cadmium and the protective effects of low-molecular-weight chitosan in the freshwater crab (Sinopotamon yangtsekiense Bott 1967)

Ruijin Li, Yanying Zhou, Jinfang Ji, +1

Aquaculture Research

EngineeringNitric OxideBioaccumulationLow-molecular-weight ChitosanRedox Biology +17

Oxidative damage, ultrastructural alterations and gene expressions of hemocytes in the freshwater crab Sinopotamon henanense exposed to cadmium

Yanying Zhou, Weixin Jing, Hans‐Uwe Dahms, +2

Ecotoxicology and Environmental Safety

BiologyUltrastructural AlterationsEcotoxicityBioactive MetalAquaculture +11

Schisandrol B promotes liver enlargement via activation of PXR and YAP pathways in mice

Ying-Yuan Zhao, Xinpeng Yao, Tingying Jiao, +10

Phytomedicine

HepatologySchisandrol BLiver PhysiologyPathologyHepatotoxicity +8

PXR mediates mifepristone-induced hepatomegaly in mice

Xinpeng Yao, Tingying Jiao, Yiming Jiang, +9

Acta Pharmacologica Sinica

Knockout MouseMedicineLiver PhysiologyHepatotoxicityPharmacology +3

Carnitine palmitoyltransferase 1C reverses cellular senescence of MRC‐5 fibroblasts via regulating lipid accumulation and mitochondrial function

Panpan Chen, Qianbin Zhang, Huizhen Zhang, +8

Journal of Cellular Physiology

Developmental BiologyBiochemistryMitochondrial FunctionLipid AccumulationMitochondrial Dysfunction +13

β-catenin/TCF4 inhibitors ICG-001 and LF3 alleviate BDL-induced liver fibrosis by suppressing LECT2 signaling

Yue Gao, Shicheng Fan, Pengfei Zhao, +6

Chemico-Biological Interactions

InflammationFibrosisSignaling Pathwayβ-Catenin/tcf4 Inhibitors Icg-001Bdl-induced Liver Fibrosis +8