Michael Lee

Diphthamide biosynthesis requires an organic radical generated by an iron–sulphur enzyme

Yang Zhang, Xuling Zhu, Andrew T. Torelli et al. · Nature · 2010 · 198 citations · Full text

Biosynthesis, Bioorganic Chemistry, Engineering +11

Selective Allosteric Inhibition of MMP9 Is Efficacious in Preclinical Models of Ulcerative Colitis and Colorectal Cancer

Derek Marshall, Susan K. Lyman, Scott McCauley et al. · PLoS ONE · 2015 · 190 citations · Full text

Inflammation, Tumor Biology, Anti-inflammatory +12

Reconstitution of ThiC in thiamine pyrimidine biosynthesis expands the radical SAM superfamily

Abhishek Chatterjee, Yue Li, Yang Zhang et al. · Nature Chemical Biology · 2008 · 143 citations · Full text

Biosynthesis, Thiamine Pyrimidine Biosynthesis, Biochemistry +7

ASK1 contributes to fibrosis and dysfunction in models of kidney disease

John T. Liles, Britton K. Corkey, Gregory T. Notte et al. · Journal of Clinical Investigation · 2018 · 137 citations · Full text

The chimeric gene CHRFAM7A, a partial duplication of the CHRNA7 gene, is a dominant negative regulator of α7*nAChR function

Tanguy Araud, Sharon Graw, Ralph Berger et al. · Biochemical Pharmacology · 2011 · 118 citations · Full text

Partial Duplication, Transcriptional Regulation, Medicine +13